An association analysis between psychophysical characteristics and genome-wide gene expression changes in human adaptation to the extreme climate at the Antarctic Dome Argus

Xu, Chao; X, Ju; Song, Dandan; Huang, Furong; Tang, Dongyang; Zou, Zhen; Zhang, C; Joshi, Trupti; Jia, Longfei; Xu, Weifeng; Kf, Xu; Q, Wang; Xiong, Yan; Z, Guo; Chen, X; Xu, Jianping; Zhong, Yi; Zhu, Yingxin; Peng, Yuanyuan; Wang, L; Zhang, X.; Jiang, Rui; D, Li; Jiang, Tao; Xu, Dongqing; Jiang, Chen-Kun

doi:10.1038/mp.2014.72

Cited by 7 publications

(5 citation statements)

References 36 publications

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“…Participants were asked to complete the Chinese version of Profile of Mood States (POMS) (McNair et al 1992), a 65-item self-report mood questionnaire which has been used in Antarctic expeditioners due to its high test-retest and internal consistency reliability (Xu et al 2003a(Xu et al , 2015. One of the subscales assesses positive affect (vigor), the other five subscales assess negative mood (tension, depression, anger, fatigue, and confusion).…”

Section: Measurementsmentioning

confidence: 99%

Different adaptations of Chinese winter-over expeditioners during prolonged Antarctic and sub-Antarctic residence

Chen

et al. 2016

Int J Biometeorol

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Prolonged residence in Antarctica is characterized by exposure to isolated, confined, and extreme (ICE) environment. Winter-over expeditioners at research stations often exhibit a complex of psychophysiological symptoms, which varied by stations and sociocultural backgrounds. To understand the different patterns of psychophysiological responses provoked by environmental stress, we conducted a longitudinal assessment of mood and endocrine function in two groups of Chinese expeditioners who were deployed to sub-Antarctic (Great Wall Station, 62°S, N = 12) and Antarctic (Zhongshan Station, 66°S, N = 16) from December 2003 to 2005. Measures of mood, thyroid function, the levels of plasma catecholamine, and circulating interleukins were obtained at departure from China, mid-winter (Antarctica), end of winter (Antarctica), and return to China, respectively. The Zhongshan Station crew experienced significant increases in fatigue, anger, tension, confusion, and decrease in free thyroxine (FT4), norepinephrine (NE), and epinephrine (E) during the winter, increase in thyrotropin (TSH) and total triiodothyronine (TT3) when returning, whereas their counterparts at Great Wall Station only experienced increased TT3 after deployment. Moreover, compared with the Great Wall Station crew, the Zhongshan Station crew exhibited greater increase in anger, greater decrease in FT4, total thyroxine (TT4), NE and E over the winter, and greater increase in TSH when returning. Chinese expeditioners who lived and worked at the Antarctic station and the sub-Antarctic station for over a year showed different change patterns in mood and endocrine hormones. Negative mood and endocrine dysfunction were positively associated with the severity of environment. The study is a supplement to scientific knowledge on psychophysiological variation under ICE environment, which has certain applied value for the development of preventive countermeasures or interventions.

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Section: Measurementsmentioning

confidence: 99%

Different adaptations of Chinese winter-over expeditioners during prolonged Antarctic and sub-Antarctic residence

Chen

et al. 2016

Int J Biometeorol

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“…伴随着高海拔而来的急性高原病(AMS) [11] 和慢性高原病 (CMS) [19,20] 等对人类适应这一极端环境的能力提出了巨大的挑战. 一些研究则表明, 即使经过较长时间的持续暴露, 人类对低氧环境的适应能力仍处于较低水平 [21,22] . 高海拔地区恶劣的自然环境、欠发达的基础设施建设水平和医疗卫生体系以及愈来愈多的人口暴露和人类较低的适应能力, 使得这一区域的人口环境风险居高不下.…”

Section: 初入高原时人体多表现为头痛、全身疲乏无unclassified

Factors contribution to oxygen concentration in Qinghai-Tibetan Plateau

et al. 2018

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“…These will assist in the evaluation of a dislocation and may also be suggestive of glenoid dysplasia, retroversion, or glenoid or humeral (RHSL) bone loss on axillary view. A thorough radiographic assessment is essential because 50% to 80% of posterior shoulder dislocations are missed on their initial assessment 14 . The true AP view should be closely evaluated for signs of a posterior dislocation, including the "light bulb sign" indicating the humeral head aligned with the axis of the shaft because of internal rotation 15 .…”

Section: Imaging Assessmentmentioning

confidence: 99%

Management of Bone Loss in Posterior Glenohumeral Shoulder Instability

Testa,

van der List,

Waterman

et al. 2024

JBJS Reviews

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» Posterior glenohumeral instability is relatively uncommon compared with anterior instability, but is becoming an increasingly recognized and surgically managed shoulder pathology.» Soft-tissue stabilization alone may not be sufficient in patients who present with substantial bone loss to the posterior glenoid and/or the anterior humeral head.» For posterior glenoid defects, posterior glenoid osteoarticular augmentation can be used, and posterior glenoid opening wedge osteotomy can be considered in cases of posterior instability with pathologic retroversion.» For humeral head lesions, several surgical treatment options are available including subscapularis transposition into the humeral head defect, autograft or allograft reconstruction, humeral rotation osteotomy, and shoulder arthroplasty.

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An association analysis between psychophysical characteristics and genome-wide gene expression changes in human adaptation to the extreme climate at the Antarctic Dome Argus

Cited by 7 publications

References 36 publications

Different adaptations of Chinese winter-over expeditioners during prolonged Antarctic and sub-Antarctic residence

Different adaptations of Chinese winter-over expeditioners during prolonged Antarctic and sub-Antarctic residence

Factors contribution to oxygen concentration in Qinghai-Tibetan Plateau

Management of Bone Loss in Posterior Glenohumeral Shoulder Instability

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