An Assist for Arthritis Studies: A 3D Cell Culture of Human Fibroblast‐Like Synoviocytes by Encapsulation in a Chitosan‐Based Hydrogel
Francesco Bisconti,
Beatrice Vilardo,
Gaia Corallo
et al.
Abstract:Osteoarthritis (OA) and Rheumatoid arthritis (RA) are the most common arthritis in which the synovium is involved, but the cellular and molecular basis of these pathologies still need better elucidation. Fibroblast‐like synoviocytes (FLS), one of the cellular elements of the synovium, play a key role in RA, an autoimmune disease characterized by joint inflammation and systemic symptoms that afflicts 1% of worldwide population. Despite articular damage starts from synovium and then proceeds involving cartilage … Show more
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