An assessment of unstimulated salivary flow rate, IgA and clinical oral dryness among active and passive smokers

Abstract

The aim of this study was to assess the impact of smoking on the whole salivary flow rate (SFR), IgA levels and clinical oral dryness (COD) among active and passive smokers. Material and Methods: The participants were categorized as active smokers (N = 54) or passive smokers (N = 163). Saliva was collected in tubes and placed in ice storage at -70°C. Salivary IgA levels were assessed in duplication using the enzyme linked immunosorbent assay (ELISA) method. Following the saliva sample collection, the subjects were assessed for COD using the COD score, SFR and caries. Chi-square test, the t-test and ANOVA were employed to compare the clinical impact of the smoking status associated with specific variables (smoking status, number of cigarettes, active caries, gender, age, COD score, IgA level and SFR). A p-value of <0.05 was considered significant. Results: Two hundred and seventeen subjects with the mean age of 32.86±6.30 years, with 145 males (66.8%) and 72 females (33.2%), were included in the study. Among the active smokers, 88.8% were males compared to 11.2% females. The active smokers had the mean age of 32.52 years,

The prevalence of xerostomia among e-cigarette or combustible tobacco users: A systematic review and meta-analysis

“…Smokers are exposed to more than 7000 chemicals per puff, which alters the salivary component, resulting in impaired oral protection 6 . Seeme et al 7 showed that active smokers had higher clinical oral dryness (COD) scores and lower salivary flow rate (SFR). Xerostomia, a subjective sensation of dry mouth, is a side effect of e-cigarette use in adults and youth 8 , 9 .…”