An Assessment of the Role of Candida Albicans and Food Yeasts in Chronic Urticaria

James, Jean; Warin, Robert P.

doi:10.1111/j.1365-2133.1971.tb14212.x

Cited by 82 publications

(28 citation statements)

References 16 publications

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“…Although yeasts including S. cerevisiae have been implicated in chronic urticaria [19], there appears to be no reports implicating this species in inhalant al lergies to fungi. Consequently, data on the allergenic nature and content of bakers' yeast are also lacking.…”

Section: Discussionmentioning

confidence: 99%

Inhalant Allergies to Fungi: Reactions to Bakers’ Yeast <i>(Saccharomyces cerevisiae)</i> and Identification of Bakers’ Yeast Enolase as an Important Allergen

Baldo

Baker

1988

Int Arch Allergy Immunol

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Forty-seven subjects diagnosed as having inhalant allergies to fungi were tested for allergic sensitivity to bakers’ yeast. Skin prick tests with yeast extract showed that 35 subjects responded with wheal reactions that were at least 3 mm while 32 subjects were regarded as clearly RAST-positive to bakers’ yeast antigens. Skin and RAST testing with purified enolase from bakers’ yeast and comparisons with the whole yeast extract showed that the enzyme is a major allergenic component of the extract. This conclusion was supported by results of electroblotting studies. RAST inhibition experiments demonstrated allergenic cross-reactivity between bakers’ yeast, bakers’ yeast enolase and Candida albicans.

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Section: Discussionmentioning

confidence: 99%

Inhalant Allergies to Fungi: Reactions to Bakers’ Yeast <i>(Saccharomyces cerevisiae)</i> and Identification of Bakers’ Yeast Enolase as an Important Allergen

Baldo

Baker

1988

Int Arch Allergy Immunol

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“…Candida albicans is another common commensal yeast in man colonizing, contrary lo F. ovale, the gastrointestinal Iracl, not the skin [9,10]. Many allergic phenomena have been connected to C. albicans, including asthma, rhinitis and urticaria [11,12]. Our previous studies have shown correlation with the severity of the AD and IgE response to C alhicans (Savolainen et al., unpublished results).…”

Section: Intruductionmentioning

confidence: 99%

Crossreacting IgE antibodies to Pityrosporum ovale and Candida albicans in atopic children

Savolainen

Broberg

1992

Clin Experimental Allergy

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Sera from 13 patients with positive Pityrosporum ovale skin prick test were analysed with IgE immunoblotting. Both P. ovale and Candida albicans antigens were used to reveal possible crossreactivity of these yeasts. Of the 13 sera, eight sera showed IgE binding to P. ovale and six sera to C. albicans. Simultaneous IgE-binding to both C. albicans and P. ovale was observed in five of these sera. The most common IgE-binding band pairs were, a 23 kD band of P. ovale and a 27 kD band of C. albicans, as one pair, and a 26 kD band and a 13 kD band, respectively, as another pair. In addition to these protein bands, simultaneous reactivity was observed to C. albicans mannan, a polysaccharide, and to a diffuse high molecular weight component of P. ovale, possibly also a polysaccharide. The five sera with simultaneous IgE-binding were analysed with RAST-inhibition, which revealed presence of crossreacting IgE-antibodies to P. ovale and C. albicans in two of these sera. Crossreacting epitopes were suggested to be located in the mannan polysaccharide of C. albicans and high molecular weight diffuse stain of P. ovale, based on the immunoblotting and RAST-inhibition patterns of the studied sera. Crossreacting sera were pooled and used as an IgE probe in CRIE and Tandem-CRIE. These experiments revealed a fused precipitin line indicating presence of a common structure of P. ovale and C. albicans. This suggested crossreactivity may imply an interesting phenomenon in atopics who are sensitized by C. albicans growth in the gastrointestinal tract and get exposed by P. ovale growing on the skin.(ABSTRACT TRUNCATED AT 250 WORDS)

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“…A large variety of substances have been incriminated on allergic or nonallergic background [18]. The importance of Candida albicans infections have been stressed by several authors [7,12] while others apparently have con sidered this aetiology less important [6,15]. Aspirin has for long time been known to aggravate or precipitate symptoms [1,10] and food additives, particularly some coal tar derivates, as for instance tartrazin, which is a yellow azo-benzene dye, has also been shown to be an important factor [8, …”

mentioning

confidence: 99%

Provocation Tests with Antiphlogistica and Food Additives in Recurrent Urticaria

Thune

A²

1975

Dermatology

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100 patients (53 women, 47 men) suffering from recurrent urticaria were tested with different food additives such as 8 dye additives, 7 preservatives and 7 antiphlogistica. In total did 62 patients react with urticaria and/or angio-oedema. 39 patients had reactions to two or more substances while 23 patients reacted to only one substance. Reactions were induced most frequently by aspirin (27/80), dextropropoxyphene (11/45) and the azo dyes tartrazin (20/96) and sunset yellow (13/86). Asthmatic symptoms occurred in 3 and purpura in 2 patients. 13 patients out of 100 reported of immediate reactions to different foods.

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An Assessment of the Role of Candida Albicans and Food Yeasts in Chronic Urticaria

Cited by 82 publications

References 16 publications

Inhalant Allergies to Fungi: Reactions to Bakers’ Yeast <i>(Saccharomyces cerevisiae)</i> and Identification of Bakers’ Yeast Enolase as an Important Allergen

Inhalant Allergies to Fungi: Reactions to Bakers’ Yeast <i>(Saccharomyces cerevisiae)</i> and Identification of Bakers’ Yeast Enolase as an Important Allergen

Crossreacting IgE antibodies to Pityrosporum ovale and Candida albicans in atopic children

Provocation Tests with Antiphlogistica and Food Additives in Recurrent Urticaria

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