An Assessment of Contributions Made by Extracranial Tissues During Cerebral Oximetry

Samra, Satwant K.; Stanley, James C.; Zelenock, Gerald B.; Dorje, Pema

doi:10.1097/00008506-199901000-00001

Cited by 59 publications

(36 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Because the wavelengths commonly used in NIRS are capable of penetrating through the superficial soft tissue layers of the head and skull with minimal absorption [1][2][3], returning scattered light can be detected and the relative oxygenation of the cerebral cortex can be calculated. When multiple wavelengths are used simultaneously, it is possible to quantify the relative concentrations of oxygenated hemoglobin (oxyHb), deoxygenated hemoglobin (deoxyHb), and their sum, total hemoglobin (total-Hb) [4,5].…”

Section: Introductionmentioning

confidence: 99%

A Functional Near-infrared Spectroscopy Study to Detect Activation of Somatosensory Cortex by Peripheral Nerve Stimulation

et al. 2007

View full text Add to dashboard Cite

To our knowledge, this is the first time functional NIRS has been used to detect activation of somatosensory cortex with peripheral nerve stimulation. While the sensitivity for detection of the functional hemodynamic response was inadequate for clinical diagnostics, these findings are uniquely important in critical care imaging in that the regional blood flow and oxygenation changes can be detected without the requirement of a volitional task. This advancement potentially expands the capability of this modality to be used in brain mapping and in the evaluation of patients with impaired cognitive or motor function at the bedside.

show abstract

Section: Introductionmentioning

confidence: 99%

A Functional Near-infrared Spectroscopy Study to Detect Activation of Somatosensory Cortex by Peripheral Nerve Stimulation

et al. 2007

View full text Add to dashboard Cite

show abstract

“…Cerebral oxygenation is also affected by many other variables. These include arterial, venous and capillary saturation, the partition ratio between the arterial and venous components of the cerebral vasculature, cerebral blood volume and possibly scalp blood flow [10,16,17]. It is possible that the bias and variability between the two monitors may in part be related to the different way in which these factors are included in the methodologies employed.…”

Section: Discussionmentioning

confidence: 99%

A comparison of cerebral oxygenation as measured by the NIRO 300 and the INVOS 5100 Near‐Infrared Spectrophotometers

Broadhead²,

et al. 2002

View full text Add to dashboard Cite

SummaryIn this study cerebral oxygenation was measured using the NIRO 300 and the INVOS 5100 spectrophotometers in 10 healthy adult volunteers, exposed to varying degrees of hyperoxia and hypoxia. The results showed similar baseline values for tissue oxygenation index and regional cerebral oxygen saturation with mean (SD) values being 64.9% (5.1) and 62.3% (6.0), respectively. The overall bias was -2.1%, with the INVOS 5100 under-reading cerebral oxygenation compared to the NIRO 300, with limits of agreement of ±14.7%. Both monitors demonstrated similar changes in response to hyperoxia and hypocapnia (coefficient of variance for F I O 2 0.45 ¼ 10.0%, F I O 2 1.0 ¼ 10.1%, hypocapnia ¼ 14.5%). The reasons for the bias and variability may relate to differences in the methodological approaches of the two monitors. The correlation between the monitors in response to changes in cerebral oxygenation implies that they may be useful as trend monitors in clinical practice.

show abstract

“…, 59, pages 453-458 . ..................................................................................................................................................................................................................... varying proportions of intra-and extracranial tissue and arterial, venous and capillary compartments [10,[20][21][22][23]. Since autoregulation keeps cerebral blood flow constant except for serious haemodynamic instability, this implicates changes in the vascular component due to vasodilation and vasoconstriction.…”

Section: Discussionmentioning

confidence: 99%

Non‐invasive monitoring of haemoglobin concentration in paediatric surgical patients using near‐infrared spectroscopy*

et al. 2004

View full text Add to dashboard Cite

SummaryWe evaluated the near-infrared spectroscopy based tissue haemoglobin index for continuous non-invasive monitoring of haemoglobin concentration during paediatric surgery. Blood samples from 40 children (from birth to 16 years old) were analysed oximetrically. From the first blood sample the tissue haemoglobin index ⁄ haemoglobin concentration coefficient was calculated for further tissue haemoglobin index-derived haemoglobin concentrations in each patient. Comparison of corresponding values revealed a bias and precision of -0.02 and 5.41 g.l )1 , respectively.Sensitivity and specificity of tissue haemoglobin index were 73.1% and 70.0%, respectively, for predicting falling haemoglobin concentration values. Currently, the tissue haemoglobin index is not suitable for monitoring haemoglobin concentration in children undergoing surgery.

show abstract

An Assessment of Contributions Made by Extracranial Tissues During Cerebral Oximetry

Cited by 59 publications

References 0 publications

A Functional Near-infrared Spectroscopy Study to Detect Activation of Somatosensory Cortex by Peripheral Nerve Stimulation

A Functional Near-infrared Spectroscopy Study to Detect Activation of Somatosensory Cortex by Peripheral Nerve Stimulation

A comparison of cerebral oxygenation as measured by the NIRO 300 and the INVOS 5100 Near‐Infrared Spectrophotometers

Non‐invasive monitoring of haemoglobin concentration in paediatric surgical patients using near‐infrared spectroscopy*

Contact Info

Product

Resources

About