An Artificial Insulin Receptor that Self-assembles and Works on a Gold Surface
Yusuke MURAI,
Hiroya SATO,
Hayate INOUE
et al.
Abstract:N' C' Gold Binding Peptide ( 3xGBP ) αCT L1CR Artifical Insulin Receptor 3GαL Self-assembling on a gold surface Insulin recognition Structural changeA novel artificial insulin receptor was developed, that can self-assemble on a gold surface and alter its structure in response to insulin recognition via partial domains of the intrinsic insulin receptor. The candidates for the artificial insulin receptor were designed by fusing the αCT segment and L1CR domain of the insulin receptor with a gold-binding peptide t… Show more
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