From discovering new drugs to autonomous laboratories in Chemistry, impact of AI will be huge in the coming years. To understand the philosophy and trend of how AI is transforming the discipline and introducing new dimensions, we start from reviewing the history of Artificial Intelligent systems in Chemistry, how it has evolved over the time and penetrated into different subdisciplines of Chemistry and is being adopted across multiple sectors of industry. We also discuss changing the job roles of the professionals and identify that new jobs will be created especially related to data management and production.