An aripiprazole related false positive amphetamine case in urine drug screen

Durmaz, Onur; Özdoğan, Merve

doi:10.1080/14659891.2020.1749951

Cited by 2 publications

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore literature also reports two cases of adult patients, a 40-year-old woman and a 23-yearold man, who were on aripiprazole therapy for bipolar disorder, also yield falsepositive results for amphetamines. In those patients the detected levels of amphetamine steadily decreased after discontinuing aripiprazole therapy [8,9]. It suggests that individuals with schizophrenia or bipolar disorder are at a higher risk of obtaining false-positive amphetamine results.…”

Section: Antipsychoticsmentioning

confidence: 99%

Guilty or not guilty? — False positive results of common medicines in drug tests: review and practical guide

2023

Folia Medica Cracoviensia

View full text Add to dashboard Cite

Drug-abuse detection tests are becoming increasingly commonplace in patient care today and provide a rapid and effective method for identifying illicit substances. Occasionally, they may yield a positive result, indicating the presence of a substance, even though the individual has not consumed the suspected drug what sometimes can significantly impact both medical and legal decisions. The study outlines the substances that can lead to false-positive drug test results for amphetamines, cannabinoids, and benzodiazepines. The study's findings have revealed pivotal insights for patients receiving chronic treatment and their primary care physicians. Notably, amphetamine assays appear to be most prone to cross-reactivity with other substances. The beta-blocker group of medications, confirmed by various studies to interfere with amphetamine assays, could pose a substantial challenge in drug screening given its widespread use. Efavirenz also warrants mention, as it frequently triggers positive results for both benzodiazepine and cannabinoid assays among its users. This research helps highlight new areas for further investigation and aims to guide clinicians in their daily practice, especially when interpreting questionable positive drug-abuse test results. This comprehensive review serves as a valuable resource for clinicians to navigate false-positive scenarios effectively and maintain the highest standard of patient care.

show abstract

Section: Antipsychoticsmentioning

confidence: 99%