In this study, based on the high-temperature characteristics of Western China tight oil reservoirs, a phenolic-larch tannin, temperature-resistant, plugging agent was synthesized by changing the mass fractions of larch tannin, double cross-linking agent, and accelerator. Young’s modulus of the dispersed gel was directly measured by an atomic force microscope, and the macroscopic plugging performance was evaluated by a physical simulation experiment of the artificially fractured natural core from Western China tight oil oilfield, thereby establishing a mapping relationship between the two. Research indicates that the formula of the high-temperature-resistant tannin system optimized by the experiment is
3.0
%
sulfonated
tannin
+
3.0
%
formaldehyde
cross
‐
linking
agent
+
1.0
%
phenol
cross
‐
linking
agent
+
0.05
%
MnS
O
4
accelerator
; the mechanical strength of the tannin gel and its plugging performance have a linear relationship. When Young’s modulus rises from 18.74 to 63.89 KPa, the plugging rate rises from 94.11% to 97.44%.