An approach to managing non-melanoma skin cancer of the nose with mucosal invasion: our experience

Chiummariello, Stefano; Dessy, Luca Andrea; Buccheri, Ernesto Maria; Gagliardi, Davide; Menichini, Giulio; Alfano, Carmine; Scuderi, Nicolò

doi:10.1080/00016480701760106

Cited by 8 publications

(7 citation statements)

References 22 publications

(35 reference statements)

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“…NMSCs are the most frequent tumours of the skin, and their incidence is higher in sun‐exposed areas. In addition, these tumours often tend to recur, even after wide excisions: SCCs’ recurrence reaches 54%, while BCCs recur in up to 35% of cases . High recurrence rates can be explained by intrinsic NMSC malignancy and by the fact that a conservative approach with narrow excision is applied in order to avoid cosmetic deformity …”

Section: Discussionmentioning

confidence: 99%

“…In the head region, the nose is the most common site where NMSCs appear . Other areas are the forehead, the scalp, the ear, and infraorbital region as a consequence of the chronic exposure to sun damage.…”

Section: Discussionmentioning

confidence: 99%

“…NMSC present quite high recurrences' rates, and we evaluated their incidence in the studies reviewed. Of them, 25 did not report data about recurrence or did not provide the complete text in English in order to evaluate this aspect .…”

Section: Discussionmentioning

confidence: 99%

“…In the head region, cutaneous malignancies occur especially in sun‐exposed areas such as the nose, representing the elective site, with the highest incidence and recurrence …”

Section: Introductionmentioning

confidence: 99%

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Skin cancers and dermal substitutes: Is it safe? Review of the literature and presentation of a 2‐stage surgical protocol for the treatment of non‐melanoma skin cancers of the head in fragile patients

Marcasciano

Mazzocchi

Kaciulyte

et al. 2018

International Wound Journal

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Non-melanoma skin cancers (NMSC) represent the most common skin tumours of the head region. We describe the use of dermal substitute in a 2-stage surgery protocol for selected fragile patients to remove NMSC of the head region. A review of the literature focusing on dermal substitutes' safety after skin tumours excision is provided. A total of 45 fragile patients with NMSC in the head region were selected and scheduled for the 2-stage surgical protocol. The first stage consisted of traditional surgical excision and immediate coverage with Hyalomatrix (Fidia Advanced Biopolymers, Abano Terme, Italy). After histology confirmed diagnosis and clearance of the margins, full-thickness skin autografts were performed. All of the patients reached complete tumour excision and wound healing. No local recurrences were registered during 24 months follow up. The 2-stage surgical therapeutic-diagnostic-reconstructive approach represents a less stressful and oncologically safe surgical protocol in selected fragile patients. When patients cannot tolerate invasive and long surgical procedures, general anaesthesia, and long hospitalisation, skin grafting following temporary skin substitute coverage can achieve oncological clearance and provide good functional and aesthetic results. The use of dermal substitutes represents a valid alternative surgical option in cases of ASA III, fragile patients non-eligible for complex reconstructive surgery. To our knowledge, this is the first paper reviewing literature focusing on dermal substitutes' applications and safety after skin tumour excision.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…In the head region, cutaneous malignancies occur especially in sun‐exposed areas such as the nose, representing the elective site, with the highest incidence and recurrence …”

Section: Introductionmentioning

confidence: 99%

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Skin cancers and dermal substitutes: Is it safe? Review of the literature and presentation of a 2‐stage surgical protocol for the treatment of non‐melanoma skin cancers of the head in fragile patients

Marcasciano

Mazzocchi

Kaciulyte

et al. 2018

International Wound Journal

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“…This cautious approach follows the rule of halting the reconstruction until confirmation of clear margins on histological examination 10. Moreover, total and subtotal nasal reconstructions are multistaged procedures that can jeopardise a potentially good outcome if performed in a non-radical field.…”

Section: Discussionmentioning

confidence: 99%

Clown nose: a case of disfiguring nodular squamous cell carcinoma of the face

Colletti

Allevi

Moneghini³

et al. 2014

BMJ Case Reports

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'Clown nose' (CN) is the common medical term referring to a reddish-brown bulge involving the tip of the nose, reminding of a clown's fake red nose. Reports about these tumours are scarce. Most reports refer to metastatic skin manifestation of systemic malignancies: this condition has been rarely described as a primary skin neoplasm. We report a case of a 31-year-old patient with a giant cutaneous squamous cell carcinoma of the nose which evolved into a CN. After ruling out genetic or immune risk factors, the patient was treated with surgical excision of the lesion and local reconstruction with good aesthetic outcome and no recurrence over a 2-year follow-up.

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