“…Indeed, in 1960, Engelhardt developed deoxofluorination of aromatic acids with sulfur tetrafluoride to obtain the corresponding trifluoromethylated products (Scheme ). Subsequently, this approach was used by other groups for the synthesis of trifluoromethyl-substituted pyridines, furans, thiazoles, uracils, pyrazoles, quinolones, etc . One of the biggest contributions to the field came from the school of the Soviet Union chemists, led by Yagupolskii .…”