An appraisal of the diagnostic value of the serological tests for toxoplasmosis

Cathie, I. A. B.

doi:10.1016/0035-9203(57)90052-4

Cited by 23 publications

(5 citation statements)

References 11 publications

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“…Although Awad (1954) and Muhlpfordt (1951) suggested that false positives to the dye test might occur in Trypanosome, Trichomonas and Sarcocystis infections, Cathie (1957) and Bakal(l959) have shown that if non-specific factors in serum are destroyed by heating these false-positive reactions do not occur. No other agent has yet been proved to give rise to positive dye tests at titres above 1/16.…”

Section: Percentage Positive Of Various Titresmentioning

confidence: 99%

Atypical Presentations of Spinal Cord Tumors in Children

Robertson

1992

J Child Neurol

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Pain is a frequent presenting symptom of spinal cord tumors in children and usually manifests as local spinal pain in the bony segments overlying the tumor. Two pediatric patients are presented in whom the diagnosis of intramedullary spinal cord tumors was delayed for many months because their pain was atypical. One had recurrent abdominal pain diagnosed as irritable bowel syndrome. The other had very abrupt paroxysmal but infrequent attacks of arm pain and no neurologic abnormalities. Possible mechanisms of their pain, as well as the other features that might have suggested the diagnosis, are discussed.

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Section: Percentage Positive Of Various Titresmentioning

confidence: 99%

Atypical Presentations of Spinal Cord Tumors in Children

Robertson

1992

J Child Neurol

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“…Sera were heated at 60 'C for 1 h to eliminate thermolabile anti-toxoplasma factors which may have been present and given rise to low-titre, false positive reactions in the dye test (Cathie, 1957).…”

Section: Dye Test (Dt)mentioning

confidence: 99%

Enzyme-linked immunosorbent assays for the measurement of specific antibodies in experimentally induced ovine toxoplasmosis

1988

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SUMMARYTachyzoites of the RH strain of Toxoplasma gondii were inoculated intravenously into sheep following which serum samples were collected at approximately weekly intervals for 9 months. The sera were examined by the toxoplasma dye test and two enzyme-linked immunosorbent assays (ELISA) specifically developed for investigations of ovine toxoplasmosis. One was an antibody class capture assay for the detection of anti-toxoplasma specific IgM, the other an indirect assay which detected anti-toxoplasma IgG.

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“…Estimates of the prevalence of toxoplasmosis in man are commonly based on immunologic tests, principally the Sabin-Feldman dye test (111) or on complement-fi xa tion (112). Cathie (113) weighed evidence concerning cross reactions ob tained by these tests with Trichomonas vaginalis, human trypanosomes, plasmodia, Salmonella typhi, and sarcosporidia. He concluded that "much of the experimental animal work on toxoplasmosis is not applicable to man," and that the dye and complement-fi xation reactions are valid for human sera.…”

Section: Faustmentioning

confidence: 99%

Parasitic Diseases of Man (Recent)

Faust¹

1958

Annu. Rev. Microbiol.

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An appraisal of the diagnostic value of the serological tests for toxoplasmosis

Cited by 23 publications

References 11 publications

Atypical Presentations of Spinal Cord Tumors in Children

Atypical Presentations of Spinal Cord Tumors in Children

Enzyme-linked immunosorbent assays for the measurement of specific antibodies in experimentally induced ovine toxoplasmosis

Parasitic Diseases of Man (Recent)

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