An Appraisal of Ancient Molecule GABA in Abiotic Stress Tolerance in Plants, and Its Crosstalk with Other Signaling Molecules

Suhel, Mohammad; Husain, Tajammul; Pandey, Aparna; Singh, Samiksha; Dubey, Nawal Kishore; Prasad, Sheo Mohan; Singh, Vijay Pratap

doi:10.1007/s00344-022-10610-8

Cited by 18 publications

(18 citation statements)

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“…GABA can promote activities of the GABA shunt, and the TCAC, antioxidant, secondary and phytohormone pathways, which in turn, reduce the stress-induced ROS level. However, the precise mechanisms whereby GABA interacts with other signaling molecules such as Ca 2+ , H 2 O 2 , PAs, salicylic acid, nitric oxide and melatonin, or with phytohormones such as ethylene, abscisic acid and auxin remain unknown ( Bor and Turkan, 2019 ; Podlešákova et al, 2019 ; Seifikalhor et al, 2019 ; Suhel et al, 2022 ).…”

Section: Postharvest Marketability Of Horticultural Commodities Is Li...mentioning

confidence: 99%

“…The exogenous application of biostimulants, including naturally occurring plant metabolites and hormones such as polyamines (PA), salicylate, jasmonate, melatonin and γ-aminobutyrate (GABA), is being studied to improve plant tolerance/resistance to abiotic and biotic stresses under both open and closed environmental conditions ( Bor and Turkan, 2019 ; Podlešákova et al, 2019 ; Akula and Mukherjee, 2020 ; Godoy et al, 2021 ; Shelp et al, 2021 ). The metabolism, transport, and signaling role(s) of GABA in plants were recently reviewed ( Shelp et al, 2021 ; Xu et al, 2021b ; Suhel et al, 2022 ). Stress-induced promotion of GABA pathways in vegetative plants, and the physiological, biochemical and molecular responses associated with enhancing stress tolerance via genetic manipulation of GABA metabolism and GABA receptors or the use of exogenous GABA were described ( Shelp et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

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γ-Aminobutyrate Improves the Postharvest Marketability of Horticultural Commodities: Advances and Prospects

2022

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Postharvest deterioration can result in qualitative and quantitative changes in the marketability of horticultural commodities, as well as considerable economic loss to the industry. Low temperature and controlled atmosphere conditions (low O2 and elevated CO2) are extensively employed to prolong the postharvest life of these commodities. Nevertheless, they may suffer from chilling injury and other physiological disorders, as well as excessive water loss and bacterial/fungal decay. Research on the postharvest physiological, biochemical, and molecular responses of horticultural commodities indicates that low temperature/controlled atmosphere storage is associated with the promotion of γ-aminobutyrate (GABA) pathway activity, with or without the accumulation of GABA, delaying senescence, preserving quality and ameliorating chilling injury. Regardless of whether apple fruits are stored under low temperature/controlled atmosphere conditions or room temperature, elevated endogenous GABA or exogenous GABA maintains their quality by stimulating the activity of the GABA shunt (glutamate GABA succinic semialdehyde succinate) and the synthesis of malate, and delaying fruit ripening. This outcome is associated with changes in the genetic and biochemical regulation of key GABA pathway reactions. Flux estimates suggest that the GABA pool is derived primarily from glutamate, rather than polyamines, and that succinic semialdehyde is converted mainly to succinate, rather than γ-hydroxybutyrate. Exogenous GABA is a promising strategy for promoting the level of endogenous GABA and the activity of the GABA shunt in both intact and fresh-cut commodities, which increases carbon flux through respiratory pathways, restores or partially restores redox and energy levels, and improves postharvest marketability. The precise mechanisms whereby GABA interacts with other signaling molecules such as Ca2+, H2O2, polyamines, salicylic acid, nitric oxide and melatonin, or with phytohormones such as ethylene, abscisic acid and auxin remain unknown. The occurrence of the aluminum-activated malate transporter and the glutamate/aspartate/GABA exchanger in the tonoplast, respectively, offers prospects for reducing transpirational water in cut flowers and immature green fruit, and for altering the development, flavor and biotic resistance of apple fruits.

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Section: Postharvest Marketability Of Horticultural Commodities Is Li...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

γ-Aminobutyrate Improves the Postharvest Marketability of Horticultural Commodities: Advances and Prospects

2022

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“…Gamma (γ)-aminobutyric acid (GABA), a non-protein amino acid, plays a critical role in plant development and stress. Several studies found that GABA can alleviate the deleterious effects of different abiotic stresses (reviewed by Sheteiwy et al, 2019;Suhel et al, 2022), and some studies found GABA improving biotic stresses also (Yu et al, 2014;Yang et al, 2017;van Rensburg and Van den Ende, 2020). Yu et al (2014) found effective alleviation of stress effects of Penicillium expansumin harvested pear fruits upon GABA treatments where GABA activated antioxidant and defense activities.…”

Section: Introductionmentioning

confidence: 99%

Effect of gamma-aminobutyric acid on resistance against stripe rust (caused by Puccinia striiformis f. sp. tritici) in wheat cultivars

Singh¹,

Zhawar²,

Pannu³

2023

JEB

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Aim: The present study was undertaken to screen wheat cultivars for resistance against stripe rust and the improvement of resistance by exogenous gamma-aminobutyric acid (GABA) under field conditions and studying two contrasting cultivars for antioxidant related defense activities at 1, 2 and 4 d of GABA, Puccinia striiformis f. sp. tritici (Pst) and GABA+Pst treatments given to one-month-old seedlings. Methodology: Wheat cultivars (PBW723, PBW725, PBW677, PBW550, PBW343, PBW621, HD2967) were grown and exposed to Puccinia striiformis f. sp. tritici (Pst) and GABA+Pst in fields and studied for yield parameters. Subsequently, two cultivars found varying in resistance (PBW725 and HD2967) were analyzed for antioxidant enzymes in leaves and roots at 1, 2, and 4 day of GABA, Pst, and GABA+Pst and water as control given to 30 days old seedlings in the greenhouse. Results: Field analysis found that the most resistant cultivar PBW725 reduced vegetative growth but not yield compared to other resistant cultivars (PBW723 and PBW677) under Pst and improved both growth and yield under GABA+Pst. GABA+Pst improved yield parameters in other cultivars also. In defense analysis, superoxide dismutase (SOD), ascorbate peroxidase (APX) and glutathione-S-transferase (GST) increased in the leaves of PBW725 while only APX increased in HD2967 at 1 d of Pst. In roots also, SOD and GST increased 2-fold in PBW725 while only GST increased 1.3-fold in HD2967 at 1 d of Pst. There was persistence of catalase (CAT), monodehydroascorbate reductase (MDHAR), and dehydroascorbate reductase (DHAR) during Pst in the leaves of PBW 725 while CAT decreased at 4 d in HD2967. In roots also, CAT and MDHAR increased at 4 days of Pstin PBW725 while DHAR decreased in HD2967. Under GABA, cultivar differences were not significant. GABA+Pst improved deficient antioxidant enzymes in HD2967. Interpretation: Energy conservation and timely regulation of antioxidant enzymes during infection was utilized by PBW725 against stripe rust. GABA deficiency can be a reason for poor regulation of antioxidants in HD2967 under Pst. GABA application improved resistance against stripe rust in wheat. Key words: Antioxidant, Ascorbate, Gamma-aminobutyric acid, Glutathione, Stripe rust, Triticum aestivum

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“…Among these substances, γ-aminobutyric acid (GABA) emerges as an important active substance with the potential to improve plant resistance to non-biological stress. GABA, known for its environmentally friendly characteristics, actively participates in various physiological activities of plants, encompassing growth, development, signal transduction, and stress response [ 10 , 11 , 12 ]. There is substantial evidence indicating that exogenous GABA can improve seed germination, plant growth and development, and enhance plant tolerance to non-biological stress, such as salt, drought, low temperature, hypoxia, and heavy metals [ 9 , 10 , 11 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…GABA, known for its environmentally friendly characteristics, actively participates in various physiological activities of plants, encompassing growth, development, signal transduction, and stress response [ 10 , 11 , 12 ]. There is substantial evidence indicating that exogenous GABA can improve seed germination, plant growth and development, and enhance plant tolerance to non-biological stress, such as salt, drought, low temperature, hypoxia, and heavy metals [ 9 , 10 , 11 , 12 , 13 ]. Additionally, GABA contributes to increased nutrient absorption and utilization efficiency by plants, such as nitrogen [ 9 , 10 , 14 , 15 ], phosphorus [ 16 ], potassium [ 17 ], and calcium [ 11 , 12 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

Exogenous γ-Aminobutyric Acid Can Improve Seed Germination and Seedling Growth of Two Cotton Cultivars under Salt Stress

Dong,

Huang,

et al. 2023

Plants

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Excessive salt content in soil has adverse effects on cotton production, especially during the germination and seedling stages. γ-aminobutyric acid (GABA) is an important active substance that is expected to improve the resistance of plants to abiotic stresses. This study focused on two cotton cultivars (Gossypium hirsutum L.: Tahe 2 and Xinluzhong 62) and investigated the impact of exogenous GABA (0, 1, 2, 3, and 4 mM) on seed germination, seedling growth, and related morphological, physiological, and biochemical indicators under salt stress (150 mM NaCl). The results showed that salt stress significantly reduced the germination rate and germination index of cotton seeds (decreased by 20.34% and 32.14% for Tahe 2 and Xinluzhong 62, respectively), leading to decreased seedling height and biomass and causing leaf yellowing. Salt stress induced osmotic stress in seedlings, resulting in ion imbalance (marked reduction in K+/Na+ ratio) and oxidative damage. Under salt stress conditions, exogenous GABA increased the germination rate (increased by 10.64~23.40% and 2.63~31.58% for Tahe 2 and Xinluzhong 62, respectively) and germination index of cotton seeds, as well as plant height and biomass. GABA treatment improved leaf yellowing. Exogenous GABA treatment increased the content of proline and soluble sugars, with varying effects on betaine. Exogenous GABA treatment reduced the Na+ content in seedlings, increased the K+ content, and increased the K+/Na+ ratio (increased by 20.44~28.08% and 29.54~76.33% for Tahe 2 and Xinluzhong 62, respectively). Exogenous GABA treatment enhanced the activities of superoxide dismutase and peroxidase, and reduced the accumulation of hydrogen peroxide and malondialdehyde, but had a negative impact on catalase activity. In conclusion, exogenous GABA effectively improved cotton seed germination. By regulating osmoprotectant levels, maintaining ion homeostasis, and alleviating oxidative stress, GABA mitigated the adverse effects of salt stress on cotton seedling growth.

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An Appraisal of Ancient Molecule GABA in Abiotic Stress Tolerance in Plants, and Its Crosstalk with Other Signaling Molecules

Cited by 18 publications

References 123 publications

γ-Aminobutyrate Improves the Postharvest Marketability of Horticultural Commodities: Advances and Prospects

γ-Aminobutyrate Improves the Postharvest Marketability of Horticultural Commodities: Advances and Prospects

Effect of gamma-aminobutyric acid on resistance against stripe rust (caused by Puccinia striiformis f. sp. tritici) in wheat cultivars

Exogenous γ-Aminobutyric Acid Can Improve Seed Germination and Seedling Growth of Two Cotton Cultivars under Salt Stress

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