An antimicrobial activity of oil extracted from Saara hardwickii

Abstract

Present research work represents antiviral and antibacterial value of body fat of Saara hardwickii commonly called as spiny tailed lizard. Oil was extracted from body fats located in the ventral region of this animal using hydrocarbons e.g., n-hexane, methanol, butanol and ethyl acetate as a solvent. The antibacterial activity of lizard oil was tested against standard as well as multi-resistant lines ofEscherichia coli, Styphalococcus aureus, Pseudomonas aeruginosa and Proteus vulgaris alone and with antibiotic ampicillin. For antibacterial potential, Ethyl acetate and Butanol solvent extract showed best zone of inhibition (7mm) with P. aeruginosa and S. aureus respectively. For antiviral potential, Butanol and Methanol extract showed best HA (Hemagglutination) titer of 04 with NDV and IBV viral strain respectively. It is concluded that lizard oil has antimicrobial potential against different pathogens strains (virus, bacteria).

Chemical composition and antimicrobial study of Crossobamon orientalis body oil

“…Current findings were in line with the research on oil extracts from Saara hardwickii but were contrary to extracts from skin of Ameiva ameiva (Linnaeus, 1758) and Tropidurus hispidus (Spix, 1825) from desert regions [ 24 , 49 ] This extract also had variable ZOI against other target bacterial strains. 1-butanol showed slight activity against drug-resistant S. aureus .…”

“…Earlier studies [ 24 , 44 ] corroborate with these antiviral findings. The IBV development was totally limited by n -hexane extract having 0 HA titer.…”

“…orientalis ) is present in the sand dunes of the Thar Desert in India and the Greater Cholistan Desert in Pakistan [ 21 , 22 ]. Several studies across world tested reptilian oil as an antimicrobial agent [ 23 , 24 ]. Understanding antibacterial potential of natural materials is crucial for developing more complex, challenging-to-adapt drugs, as well as properly studying their properties and confirming their effectiveness [ 25 ].…”

Antimicrobial activity, antioxidant and chromatographic analysis of Varanus griseus oil extracts

“…The extract was e ciently active against growth of NDV and IBV and comparatively less active against H9N2 and IBDV viruses. Current ndings are in accordance with earlier work carried on n-Hexane extract of Saara hardwickii body oil(Arshad et al 2022). GC-MS analysis of n-Hexane extract displayed bioactive compounds viz.…”

In vitro antifungal and antibacterial potentials of organic extracts of Avicennia marina collected from Rabigh Lagoon, Red Sea Coasts in Saudi Arabia

“…The steps in this technique were completed in accordance with (Balouiri et al, 2016). Freshly generated standard cell concentrations of fungus studies on natural medicinal substances (Arshad et al, 2024;Compean and Ynalvez, 2014;Ananthavalli and Karpagam, 2017). A growing number of pharmaceutical corporations and researchers have turned their attention to therapeutic plants in the last few decades.…”