2023
DOI: 10.1039/d3cc03128d
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An antibacterial conjugate of carbon nanohorns for NIR-light mediated peri-implantitis treatment

Eri Hirata,
Yuta Takano,
Daisuke Konishi
et al.

Abstract: TThis study developed a novel antibacterial conjugate based on carbon nanohorns for peri-implantisis, an inflammatory disease around dental implants, which may result in failing implants by bone loss around them....

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(1 citation statement)
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“…The above results guaranteed that rTPA@ms-QD possesses both abilities of bright photolabeling and photoinduced 1 O 2 generation, which is useful for medical applications of photo-mediated cancer or bacterial killing. 46,57 Thus, rTPA@ms-QD was tested in a spheroid, a living cellular assembly consisting of more than hundreds of cells that mimic realistic tissues. 58 Because spheroids are usually much thicker specimens than conventionally cultured cells on a dish, higher luminescence is required to clearly visualize the photo label under microscopic observations.…”
Section: Resultsmentioning
confidence: 99%
“…The above results guaranteed that rTPA@ms-QD possesses both abilities of bright photolabeling and photoinduced 1 O 2 generation, which is useful for medical applications of photo-mediated cancer or bacterial killing. 46,57 Thus, rTPA@ms-QD was tested in a spheroid, a living cellular assembly consisting of more than hundreds of cells that mimic realistic tissues. 58 Because spheroids are usually much thicker specimens than conventionally cultured cells on a dish, higher luminescence is required to clearly visualize the photo label under microscopic observations.…”
Section: Resultsmentioning
confidence: 99%