An anti-inflammatory and anti-microbial flavone glycoside from flowers of Cleome viscosa

Senthamilselvi, M. M.; Devarayan, Kesavan; Sulochana, N.

doi:10.1186/2191-2858-2-19

Cited by 28 publications

(16 citation statements)

References 15 publications

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“…It is known that the flavonol contents may be affected by a wide range of environmental conditions including temperature, soil, light levels, nutritional conditions. It is obvious that, kaempferol 3,7-dirhamnoside found in high percentages in C. viscosa which is agreement with the result of Senthamilselvi et al, 2012. Furthermore, quercetin 3,7-dirhamnoside and kaempferol 3-rhamnoside-7glucoside in C. brachycarpa supported by results of Sharaf et al 1997.…”

Section: Peroxidases (Prx)supporting

confidence: 84%

“…which were identified as kaempferol-3-O-glucoside, rutin, kaempferol, and luteolin-7-o-glucoside. Furthermore, Quercetin 3-o-(2-acetyl)-glucoside reported in Cleome viscosa L. by Senthamilselvi et al, 2012. Molecular systematics for 22 taxa belonging to 9 tribes of Brassicaceae in Egypt using isoenzymes electrophoretic techniques were studied by Hasan (2009).…”

Section: Introductionmentioning

confidence: 99%

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Flavonoids and isoenzymes as chemotaxonomic markers in Cleome L.(Cleomaceae Bercht. & J.Presl)

Kasem¹,

Fatahy²

2016

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These studies were conducted on the twoflavonoid compounds of quercetin and kaempferol in addition electrophoretic studies of esterase and peroxidase isoenzymes by SDS-polyacrylamide gel electrophoresisfor five CleomeL. species. Extraction of these flavonoids was carried out using 90% ethanol and 85% methanol. Identification and quantification of quercetin and kaempferol was done using thin Layer chromatography (TLC) and further augmented using high performance liquid chromatography (HPLC) and then isolated,purified and identified using melting point (M.P.) and infrared spectroscopy (IR).eightquercetinand seven kaempferol compounds are isolated and identified with different percentages. Electrophoretic patterns of two isoenzymes ofesterases (Est) and peroxidases (Prx) considered a good taxonomicmarker techniques. A total 45 esterase and peroxidase bands obtained scanning the gels. The highest combined esterase and peroxidase bands (13 bands) are found in C.scaposa DCwhereasthe lowest seven bands are recorded in C. paradoxa B.BR.35 obtained data of two flavonoid compounds and two isoenzymeswere subjected to numerical analysis which separated the studied species into two groups, the first has C.gynandra. and C. viscosa L., the second group included three species of C. scaposa DC, C. brachycarpa . and C. paradoxa.

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Section: Peroxidases (Prx)supporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Flavonoids and isoenzymes as chemotaxonomic markers in Cleome L.(Cleomaceae Bercht. & J.Presl)

Kasem¹,

Fatahy²

2016

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“…The seeds are occasionally used as a condiment in curries. 7,8 Previous phytochemical investigations of C. viscosa have yielded a flavonol 9 , dipyridodiazepinone derivative 10 , quercetin 3-O-P-d-glucopyranoside 7-O-a-l-rhamnopyranoside 11,12 , quercetin 7-O-al-rhamnopyranoside 13 , astragalin 14 , isorhamnetin 3-O-b-D-glucopyranoside 15 , and lactam derivative 16 which possessed anticancer properties.…”

Section: Introductionmentioning

confidence: 99%

Isolation and Structural Elucidation of Allantoin a Bioactive Compound from Cleome viscosa L.: A Combined Experimental and Computational Investigation

Lakshmanan¹,

Sivaraj²,

Ammar³

et al. 2019

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Allantoin, a crystalline compound was isolated from the methanolic extract of Cleome viscosa and it was reported for first time from this plant. The structure of Allantoin was elucidated by single crystal XRD and it was further confirmed through FTIR and ESI-MS spectroscopy techniques. It was crystallized in monoclinic crystal system with the space group P2i/c. Electronic structure characterization of the isolated Allantoin was done through density functional theory calculation. The atomic charges, dipole moment, frontier molecular orbital and the electrostatic potential map of the molecule in the gaseous phase and in the active site have also been analyzed. The optimized geometry was used for molecular docking to identify the possible binding mode. Furthermore, the in vitro antibacterial activity of the isolated Allantoin against Gram-positive and Gram-negative bacteria was evaluated. Maximum Inhibitory Concentrations (MIC) of isolated Allantoin results showed 4 µg/mL for B. subtilis and 8 µg/mL for S. aureus, E. coli and K. pneumoniae.

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“…In other study C. viscosa shows very high inhibition zone diameters against Aeromonas hydrophila and Bacillus cereus 34 . Flavonoid glycoside that is, quercetin 3-0-(2 "-acetyl) -glucoside isolated from C. viscosa shown antimicrobial activity towards the grampositive bacteria Mainly to Staphylococcus aureus 35 . Both the leaves and the stems of CV shown anti-bacterial and antifungal activity due to the presence of a 14-membered diterpene cembranoid.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Cleome viscose: A Review on Ethnobotany and Pharmacology Uses

Singh

Mehta

Yashwant

2017

IJPQA

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Herbal medicine is the oldest form of health care system known to mankind. Herbs had been used by all cultures through history. Herbs are the potential source of chemical constituents that have a high therapeutic value. Herbal medicines are now in high demand in the developing world for primary health care not because they are cheap but also for better cultural acceptance, better compatibility with the human body and minimal side effects. This review summarizes the research on Cleome viscose Linn. (Capparidaceae), commonly known as "wild mustard or dog", is an annual sticky herb that is found in all plains of India and throughout the tropics of the world. The whole plant and its parts (leaves, seeds, and roots) are widely used in traditional and folk medicine systems. In traditional systems of medicine, the plant is reported to have beneficial effects such as anthelmintic, antiseptic, carminative, antiscorbutic, sudorific, febrifuge and cardiac stimulant. Following the various traditional claims for the use of C. viscosa (CV) as a cure for numerous diseases, researchers have made considerable efforts to verify their usefulness through scientific pharmacological examinations. Pharmacological studies have shown that CV has several notable biological activities, such as anthelmintic, antimicrobial, analgesic, antiinflammatory, immunomodulatory, antipyretic, psychoprotein, wound healing, antimalarial, antiemetic, antitumor, antioxidant, antidiarrheal and hepatoprotective. The present review is an effort to consolidate the traditional, ethnobotanical, and pharmacological information available in C. viscosa.

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An anti-inflammatory and anti-microbial flavone glycoside from flowers of Cleome viscosa

Cited by 28 publications

References 15 publications

Flavonoids and isoenzymes as chemotaxonomic markers in Cleome L.(Cleomaceae Bercht. & J.Presl)

Flavonoids and isoenzymes as chemotaxonomic markers in Cleome L.(Cleomaceae Bercht. & J.Presl)

Isolation and Structural Elucidation of Allantoin a Bioactive Compound from Cleome viscosa L.: A Combined Experimental and Computational Investigation

Cleome viscose: A Review on Ethnobotany and Pharmacology Uses

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