“…The software anthropomorphic phantoms developed at the University of Pennsylvania have been used in various applications, including the validation and optimization of digital breast tomosynthesis (DBT) reconstruction methods [18]- [20], DBT image denoising methods [21], [22], ultrasound tomography (UST) reconstruction and segmentation methods [23], [24], analysis of power spectra descriptors in simulated phantom DBT images [10], [25], [26], analysis of texture properties in phantom digital mammography (DM) and DBT images [27], [28], and analysis of tumor detectability in DBT [29]- [31]. Physical versions of the 3D anthropomorphic software phantom have also been produced [32]- [36].…”