An anthraquinone derivative from Cassia italica

Kazmi, Mehdi Hussain; Malik, Abdul; Hameed, Saira; Akhtar, Nasima; Ali, Samina

doi:10.1016/s0031-9422(00)89812-x

Cited by 64 publications

(36 citation statements)

References 6 publications

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“…40 The potential for developing antimicrobials from higher plants appears rewarding, as it will lead to the development of a phytomedicine to act against microbes. Many plants have been used because of their antimicrobial traits, which are due to compounds synthesized in the secondary metabolism of the plant, such as phenols, 41 essential oils, 42 terpenoids, 43,44 alkaloids, 24 and flavonoids. 45 …”

Section: Discussionmentioning

confidence: 99%

Determination of Antimicrobial Activity of Sorrel (Hibiscus sabdariffa) onEsherichia coliO157:H7 Isolated from Food, Veterinary, and Clinical Samples

Fullerton

Khatiwada

Johnson

et al. 2011

Journal of Medicinal Food

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The use of medicinal plants as natural antimicrobial agents is gaining popularity. Sorrel (Hibiscus sabdariffa) is widely used for the treatment of diseases. The objective of this study was to investigate the antimicrobial activity of sorrel on Escherichia coli O157:H7 isolates from food, veterinary, and clinical samples. Phenolics of the calyces were extracted from 10 g of ground, freeze-dried samples using 100 mL of 80% aqueous methanol. Concentrations of 10%, 5%, and 2.5% methanol extract of sorrel were investigated for its antimicrobial activity. Inhibition zones were indicated by a lack of microbial growth due to inhibitory concentrations of sorrel diffused into semisolid culture medium beneath the sorrelimpregnated disk. The results of this experiment showed that the most potent sorrel concentration was 10%, then 5%, and finally 2.5%. The overall mean zone of inhibition for the sorrel extract was 12.66 mm for 10%, 10.75 mm for 5%, and 8.9 mm for 2.5%. The highest inhibition zones (11.16 mm) were observed in veterinary samples, and the lowest (10.57 mm) in the food samples. There were significant (P < .05) differences among mean zones of inhibition found in the food, veterinary, and clinical sources. Based on the source of samples and concentration of sorrel extract, the lowest mean inhibition was 7.00 -0.04 mm from clinical samples, and the highest was 15.37 -0.61 mm from a food source. These findings indicated that sorrel was effective at all levels in inhibiting E. coli O157:H7; thus it possesses antimicrobial activity and hold great promise as an antimicrobial agent.

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Section: Discussionmentioning

confidence: 99%

Determination of Antimicrobial Activity of Sorrel (Hibiscus sabdariffa) onEsherichia coliO157:H7 Isolated from Food, Veterinary, and Clinical Samples

Fullerton

Khatiwada

Johnson

et al. 2011

Journal of Medicinal Food

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show abstract

“…These phytocompounds mainly targeting the cell wall of bacteria (Cowan, 1999) inactivates microbial enzymes, cell wall protein (Jones et al, 1994) and also cause loss of cellular function (Kazmi et al, 1994). Hence, the methanolic extract shows maximum antibacterial activity against E. coli (8-10mm) at 10, 15, 20 and 25 mg/ml concentration of plant extracts.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical Profiling, Antibacterial Potential and GC-MS Analysis of Methanol Leaf Extract of Enicostemma axillare

Nila¹,

Karthikeyan²

2017

Int.J.Curr.Microbiol.App.Sci

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“…Research has confirmed that its chemical composition is the same as that of C. angustifolia. 9 The leaves and fruit are rich in sennosides (anthraquinone glycosides), 30 which are broken down in the colon and cecum by the gut flora to the active rhein anthrone. This stimulates peristalsis.…”

Section: Laxa Cassia (Senna Italica)mentioning

confidence: 99%