An animal model of hypnotic pain attenuation

Castiglioni, J. A.; Russell, M. I.; Setlow, Barry; Young, Ki-Won; Welsh, Jane; Steele-Russell, I.

doi:10.1016/j.bbr.2008.08.020

Cited by 5 publications

(1 citation statement)

References 36 publications

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“…One of the ways it does this is by the release of endogenous opiates. These substances produce various degrees of analgesia and anesthesia and allow the organism to better cope with acute stress; they are a soothing balm for body and soul alike (see Castiglioni et al, 2009; da Silva & Menescal-de-Oliveira, 2006; Leite-Panissi, Brentegani, & Menescal-de-Oliveira, 2004; Leite-Panissi, Rodrigues, Brentegani, & Menescal-De-Oliveira, 2001; Porro & Carli, 1988). Part of this “antinociceptive machinery” may have been transferred into human sleep as opioids seem to play a certain, albeit far from clarified, role in the human sleep cycle (Dimsdale, Norman, DeJardin, & Wallace, 2007; Greco et al, 2008).…”

Section: Auxiliary Factsmentioning

confidence: 99%

The origin of REM sleep: A hypothesis.

Tsoukalas

2012

Dreaming

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This article presents a new theory about the origin of REM sleep. REM is an integral part of the human sleep cycle and the neurological substrate most consistently associated with dreams and dream recall. According to this thesis, REM sleep evolved out of a primordial defensive reflex: tonic immobility. This reflex, sometimes also called death-feigning or animal hypnosis, is usually the last line of defense against an attacking predator. Tonic immobility, common in both vertebrates and invertebrates, has a number of neuroanatomical and behavioral attributes that overlap with those of REM sleep. This overlap is suggestive of an evolutionary kinship. The article presents conceptual arguments and empirical facts in support of this relationship.

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