An anatomical study of the myelination of human laryngeal nerves

Abstract

These findings support those of previous studies, and provide further evidence against the historical plexus theory of laryngeal nerve morphology. The differences in the degree of myelination, both within and between the human laryngeal nerves, may have clinical consequence regarding recovery of function following nerve injury.

Electrode fabrication and interface optimization for imaging of evoked peripheral nervous system activity with electrical impedance tomography (EIT)

“…In this work we show that nerve cuffs with the optimized PEDOT:pTS coating were able to localize impedance changes corresponding to observed compound activity that was likely originating from the motor fibers in the recurrent laryngeal nerve. The timing of the compound action potential at approximately 8-10 ms after stimulation over a distance of approximately 1 meter suggests that the fibers imaged here are A-alpha motor fibers with a conduction velocity in the realm of 100-120 m s −1 , a result which is consistent with previous histological studies of the recurrent laryngeal nerve [30,43]. The reconstructed images were consistent across two separate animals with three trials in each animal.…”

“…This yielded a compound action potential approximately 8-10 ms after stimulation (figure 7(b)). The conduction velocity (~100 m s −1 ) of this activity caused by the stimulation of the recurrent laryngeal nerve matches the expected conduction velocity of the predominant fiber type (A-alpha) that constitutes the nerve in humans [30]. Further analysis of the recorded EIT data revealed a distinct impedance change directly correlating to the timing of the compound action potential of the recurrent laryngeal nerve (figure 7…”