An analysis of the specificity and the syndromal correlates of verbal memory impairments in schizophrenia

Moritz, Steffen; Heeren, Deike; Andresen, Burghard; Krausz, Michael

doi:10.1016/s0165-1781(00)00241-9

Cited by 61 publications

(29 citation statements)

References 30 publications

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“…Similarly, performance on the RAVLT is significantly impaired in schizophrenia, with deficits in repletion of the list following interference (list 7) correlating most strongly with negative symptoms (Moritz et al, 2001). These findings therefore support use of D-serine for treatment of memory impairments as well as negative symptoms in schizophrenia, especially since the D-serine binding site does not appear to be saturated under physiological conditions Kantrowitz and Javitt, 2010).…”

Section: Discussionmentioning

confidence: 60%

Behavioral and cognitive effects of the N-methyl-d-aspartate receptor co-agonist d-serine in healthy humans: Initial findings

Levin

Dor-Abarbanel²,

Edelman³

et al. 2015

Journal of Psychiatric Research

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Section: Discussionmentioning

confidence: 60%

Behavioral and cognitive effects of the N-methyl-d-aspartate receptor co-agonist d-serine in healthy humans: Initial findings

Levin

Dor-Abarbanel²,

Edelman³

et al. 2015

Journal of Psychiatric Research

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“…Additional studies have linked performance deficits to disorganization syndrome in schizophrenic patients on task of cognitive deficits with shifting set and interference tasks 80-82. Syndrome dimensions reflecting psychomotor deficits have been linked to verbal fluency and memory measures 81, 83-85. O'Leary et al86 showed a relationship between cognitive deficits and disorganization and negative syndrome.…”

Section: Schizophrenic Disordermentioning

confidence: 99%

Comorbid Mood, Psychosis, and Marijuana Abuse Disorders: A Theoretical Review

Wilson

Cadet

2009

Journal of Addictive Diseases

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There is a need to bridge the gap between the fields of addiction psychiatry and general psychiatry in order to effectively treat co-morbid substance abuse and psychiatric disorders. This alarming epidemic transcends communities and severely impacts healthcare worldwide yielding poor treatment outcomes and prognoses for afflicted patients. Because substance abuse can acerbate and/or trigger psychosis and mood disorders, it is important to keep these issues in the forefront when evaluating patients. In order to address some of the complications stemming from not enough interactions between various groups of practitioners, this review addresses the neurobehavioral effects of cannabis use and their impact on patients who suffer from psychotic or affective disorders. The hope is that this paper will serve as a spring board for further discussions among practitioners who treat these patients. Greater interactions between caretakers are bound to impact the care of our patients in a very positive way.

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“…These findings support the notion of the timelimited role of the hippocampus in the formation and maintenance of memory. As such, applying a similar paradigm to individuals with schizophrenia may allow us to identify the neuroanatomical regions of dysfunction which figure most prominently in the deficits exhibited by patients, who show evidence of impairments in both delayed and immediate recall (see, e.g., Egeland et al 2003;Moritz et al 2001), which would argue more strongly for dysfunction of MTL regions during initial encoding, but recruitment of ancillary regions in a temporally graded manner. Determining whether just such a temporal gradient across neuroanatomical regions can be identified in patients will elucidate yet another aspect of the integrity of their memory systems, with specific regard to their storage processes.…”

Section: Introductionmentioning

confidence: 99%

Episodic Memory in Schizophrenia

Leavitt

Goldberg

2009

Neuropsychol Rev

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Episodic memory impairments in individuals with schizophrenia have been well documented in the literature. However, despite the abundance of findings, constituent cognitive, neural, behavioral, and genetic components of the deficits continue to elude full characterization. This review provides a characterization of these deficits by organizing findings within three frameworks of interest: 1) neuroanatomical; 2) genetic; and 3) behavioral. Within each approach, evidence from imaging studies as well as behavioral studies is examined. The hope is that by synthesizing the cognitive science paradigms, molecular genetic neurophysiological findings, and computational algorithms applied to medial temporal lobe subregions, we will be able to expand our understanding of the types of compromises in episodic memory systems of individuals with schizophrenia.

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An analysis of the specificity and the syndromal correlates of verbal memory impairments in schizophrenia

Cited by 61 publications

References 30 publications

Behavioral and cognitive effects of the N-methyl-d-aspartate receptor co-agonist d-serine in healthy humans: Initial findings

Behavioral and cognitive effects of the N-methyl-d-aspartate receptor co-agonist d-serine in healthy humans: Initial findings

Comorbid Mood, Psychosis, and Marijuana Abuse Disorders: A Theoretical Review

Episodic Memory in Schizophrenia

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