1964
DOI: 10.1152/jappl.1964.19.1.97
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An analysis of pressure-volume characteristics of the lungs

Abstract: By analysis of the retractive forces of the lungs it was found that the pressure-volume characteristics of the lungs may be expressed by an exponential function. The curve described by such expression could be fitted to the experimental data obtained in 20 normal subjects. A half-inflation pressure (h) was defined which makes possible the evaluation of the retractive forces of the lungs by a measurement independent of lung size and accounting for known curvilinearity. H is a useful index of the stiffness of th… Show more

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Cited by 309 publications
(165 citation statements)
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“…A distributed time-varying pressure load was applied to the surface of the FE lung model. Pressure amplitudes at each breathing phase were evaluated from the parametrized P-V curve 52 and the mean P-V curve 53 shown in Fig. 5.…”
Section: Iib Physiological Respiratory Motion Modelingmentioning
confidence: 99%
See 1 more Smart Citation
“…A distributed time-varying pressure load was applied to the surface of the FE lung model. Pressure amplitudes at each breathing phase were evaluated from the parametrized P-V curve 52 and the mean P-V curve 53 shown in Fig. 5.…”
Section: Iib Physiological Respiratory Motion Modelingmentioning
confidence: 99%
“…Though in Fig. 5, the value of volume of tidal volume ͑TV͒ and pressure was used as 500 ml and 10 cm H 2 O for illustration, the pressures at EI are evaluated by the mean P-V curve 53 and the change of scaled pressure over volume are fitted by the parameterized P-V curve. 52 A tumor-bearing lung is modeled as an elastic medium ⍀ consisting of N homogeneous isotropic subdomains in the finite-element model of ABAQUS.…”
Section: Iib Physiological Respiratory Motion Modelingmentioning
confidence: 99%
“…A cannula was inserted and the mice were attached to a ventilator equipped with a pressure and volume (flow) transducer (flexiVent; SciReq). Static compliance measurements were obtained from dynamic pressure volume curves using the Salazar-Knowles equation (34).…”
Section: Measurement Of Lung Functionmentioning
confidence: 99%
“…(2) Equation (2) included total lung capacity (TLC) and was designed to fit the whole range of lung volumes, whereby former models fitted data only for lung volumes above functional residual capacity [5]. Originally, TLC is the amount of gas in the lungs after a voluntary maximal inspiration.…”
Section: Introductionmentioning
confidence: 99%