The use of remote-control locomotives has become prevalent in most major rail yards in North America. Despite their increased use, they are limited by the functionality and current design of the operator control unit. Human factors research has identified interface design issues with the controller, emphasizing the need to rethink a new generation of remote-control units that can accommodate the growing needs of operational functionality through effective interface design. Towards that goal, we present the preliminary findings of an exploratory study comparing the functional effectiveness and usability of two types of remote-control modalities – a traditional gaming controller and a multi-touch tablet – to drive a locomotive. Initial findings indicate that the game controller modality is preferred over multi-touch, with low variation among participants. However, the preference of control mode (i.e., vehicle power or speed command input) was different for the two modalities. These initial findings are the first of their kind in identifying initial design considerations for future remote locomotive operation and in comparing the use of traditional gaming and multi-touch controllers.