Keywords:Breast screening Effective risk FFDM MGD Thermoluminescence dosimetry a b s t r a c t Background and purpose: The performance of mammography screening programmes is focussed mainly on breast cancer detection rates. However, when the benefits and risks of mammography are considered, the risk of radiation-induced cancer is calculated for only the examined breast using Mean Glandular Dose (MGD). The risk from radiation during mammography is often described as low or minimal. This study aims to evaluate the effective lifetime risk from full field digital mammography (FFDM) for a number of national screening programmes. Material and Methods: Using an ATOM phantom, radiation doses to multiple organs were measured during standard screening mammography. Sixteen FFDM machines were used and the effective lifetime risk was calculated across the female lifespan for each machine. Once the risks were calculated using the phantom, the total effective lifetime risk across 48 national screening programmes was then calculated; this assumed that all these programmes use FFDM for screening. Breast cancer morbidity differs significantly between regions and according to the American Cancer Society (ACS), 3 39% of breast cancer cases were recorded in Asia while in Europe and North America, the figures were 28% and 15%, respectively. Early diagnosis and treatment of breast cancer is the key to reduce mortality.
4Randomised screening trials using mammography illustrated that screening can reduce breast cancer mortality by 15e20%. 5 Since mammography is seen as a cost-effective technique for early detection of breast cancer, it remains the recommended modality for both screening and diagnosis. The performance of any screening programme should be assessed by three parameters; sensitivity, specificity, and positive predictive value. 7,8 The calculation of these parameters depends on three related quantities; mammography false negatives which represents mammography's inability to detect all breast cancers, mammography false positives which may result in extra examinations and undesired anxiety for women, and overdiagnosis of low risk breast cancers that may never cause health problems.9,10