An amphipathic helix facilitates direct membrane binding of Mycoplasma FtsZ
Soumyajit Dutta,
Sakshi Poddar,
Joyeeta Chakraborty
et al.
Abstract:Cell division in bacteria is initiated by constriction of the Z-ring comprising two essential proteins FtsZ and FtsA. Despite our knowledge about the crucial function of the Z-ring in bacterial division, the precise roles and mechanism of how FtsZ and FtsA drive cell constriction remain elusive. FtsZ/FtsA in wall-less bacteria like mycoplasmas is an ideal model system for obtaining mechanistic insights into Z-ring constriction in the absence of cell wall machinery. In this study, we have analyzed FtsZ and FtsA… Show more
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