An Alternative Source of Autograft Bone for Spinal Fusion

Nichols, Tann A.; Sagi, H. Claude; Weber, Timothy G.; Guiot, Bernard H.

doi:10.1227/01.neu.0000317390.21927.ad

Cited by 21 publications

(21 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The RIA has been reported as a source of bone graft with supportive experimental [17] and clinical studies [5,[7][8][9] and case reports [6,[20][21][22][23]. Direct grafting of harvested RIA bone fragments, in addition to 'autografting' alone has been shown to improve stiffness (1.21 Nm compared with 0.48 Nm; P=0.029) and strength (14.09 Nm compared with 6.94 Nm; P=0.029) in a sheep model [19].…”

Section: Harvest Of Bone Graft and Mscsmentioning

confidence: 99%

Reamer-irrigator-aspirator indications and clinical results: a systematic review

Cox

Jones

McGonagle

et al. 2011

International Orthopaedics (SICOT)

125

View full text Add to dashboard Cite

Background The 'reamer-irrigator-aspirator' (RIA) is an innovation developed to reduce fat embolism (FE) and thermal necrosis (TN) that can occur during reaming/ nailing of long-bone fractures. Since its inception its indications have expanded to include the treatment of long-bone osteomyelitis and as a harvester of bone graft/ mesenchymal stem cells (MSCs). Methods This study involved a systematic review, via Pubmed® and Google Scholar®, of English language sources (nine non-clinical studies, seven clinical studies and seven case reports) using the keywords: 'reamer', 'irrigator', 'aspirator' (1st May 2010). Sources were reviewed with reference to the RIAs efficacy in (1) preventing FE/TN, (2) treating long-bone osteomyelitis, (3) harvesting bone graft/MSCs, and (4) operating safely. Experimental data supports the use of the RIA in preventing FE and TN, however, there is a paucity of clinical data. Conclusions The RIA is a reliable method in achieving high volumes of bone graft/MSCs, and high union rates are reported when using RIA bone-fragments to treat nonunions. Evidence suggests possible effectiveness in treating long-bone osteomyelitis. The RIA appears relatively safe, with a low rate of morbidity provided a meticulous technique is used. When complications occur they respond well to conventional techniques. The RIA demands further investigation especially with respect to the optimal application of MSCs for bone repair strategies.

show abstract

Section: Harvest Of Bone Graft and Mscsmentioning

confidence: 99%

Reamer-irrigator-aspirator indications and clinical results: a systematic review

Cox

Jones

McGonagle

et al. 2011

International Orthopaedics (SICOT)

125

View full text Add to dashboard Cite

show abstract

“…Several investigators noted that the aspirate from the reaming system was laden with bioactive substrates (eg, osteoblasts) and growth factors (eg, bone morphogenetic protein-2 [BMP-2]) after performing cell cultures and flow cytometry [8,9,18,22,25,26]. The RIA system has been used clinically to procure bone graft from the femur; however, few studies describe its clinical use [12,13,15,24].…”

Section: Introductionmentioning

confidence: 99%

Bone Graft Harvest Using a New Intramedullary System

Belthur

Conway

Jindal

et al. 2008

Clinical Orthopaedics &Amp; Related Research

147

View full text Add to dashboard Cite

Obtaining autogenous bone graft from the iliac crest can entail substantial morbidity. Alternatively, bone graft can be harvested from long bones using an intramedullary (IM) harvesting system. We measured bone graft volume obtained from the IM canals of the femur and tibia and documented the complications of the harvesting technique. Donor site pain and the union rate were compared between the IM and the traditional iliac crest bone graft (ICBG) harvest. Forty-one patients (23 male, 18 female) with an average age of 44.9 years (range, 15-78 years) had graft harvested from long bones using an IM harvest system (femoral donor site, 37 patients; tibial donor site, four patients). Forty patients (23 male, 17 female; average age, 46.4 years; range, 15-77 years) underwent anterior ICBG harvest. We administered patient surveys to both groups to determine pain intensity and frequency. IM group reported lower pain scores than the ICBG group during all postoperative periods. Mean graft volume for the IM harvest group was 40.3 mL (range, 25-75 mL) (graft volume was not obtained for the ICBG group). Using an intramedullary system to harvest autogenous bone graft from the long bones is safe provided a meticulous technique is used.

show abstract

“…Factors include amount of pain, infection rate, amount of bone graft, and ease of the procedure. Intramedullary bone graft harvest with the Reamer-Irrigator-Aspirator (RIA) system (Synthes Inc., USA, West Chester, PA) was developed as an alternative to common bone graft options such as iliac crest bone graft and synthetic bone substitutes [4,21,25,33,44]. Th e origin of this procedure can be traced to Stürmer at al.…”

Section: Introductionmentioning

confidence: 99%

“…Despite these developments, autogenous bone graft can still be considered the gold standard in defect reconstruction because of its intrinsic osteogenetic activity [1,8,9,15,24,33,39,46,51]. Th e use of collected intramedullary reaming debris has been investigated in several trials and was found to be safe and comparable to other sources of bone graft [4,8,13,14,19,20,33,36,37,42].…”

Section: Introductionmentioning

confidence: 99%

Bone graft harvesting using the RIA (reaming irrigation aspirator) system – a quantitative assessment

Kovar

Wozasek

2011

Wien Klin Wochenschr

View full text Add to dashboard Cite

On the basis of our present results, harvesting intramedullary bone graft with the RIA system appears to be an innovative technique for bone grafting in limb reconstruction. A significantly greater quantity of bone graft was harvested from the femora than the tibiae (p = 0.007). No significant differences among age, sex, body weight, bone length, or BMI were observed. Our results showed that a sufficient quantity in weight of autogenous bone graft could be obtained using the RIA system.

show abstract

An Alternative Source of Autograft Bone for Spinal Fusion

Abstract: Femoral reaming provides an alternative source of autograft bone when other sources are unavailable.

Cited by 21 publications

References 20 publications

Reamer-irrigator-aspirator indications and clinical results: a systematic review

Reamer-irrigator-aspirator indications and clinical results: a systematic review

Bone Graft Harvest Using a New Intramedullary System

Bone graft harvesting using the RIA (reaming irrigation aspirator) system – a quantitative assessment

Contact Info

Product

Resources

About