An alternative method to measure the diffusing capacity of the lung for carbon monoxide in infants

Praca, Eduardo; Tiller, Christina; Kisling, Jeffrey; Tepper, Robert S.

doi:10.1002/ppul.23926

Cited by 2 publications

(2 citation statements)

References 7 publications

(31 reference statements)

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“…The technique most commonly used is the single breath method which requires a 10 s breath hold and may be difficult for preschool children and for very tachypnoeic patients. Methods have been developed for measuring single breath T LCO in infants and toddlers, but these are not widely used or routinely available [29,67].…”

Section: Diffusing Capacity Measurementmentioning

confidence: 99%

Pulmonary function testing in children's interstitial lung disease

et al. 2020

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The use of pulmonary function tests (PFTs) has been widely described in airway diseases like asthma and cystic fibrosis, but for children's interstitial lung disease (chILD), which encompasses a broad spectrum of pathologies, the usefulness of PFTs is still undetermined, despite widespread use in adult interstitial lung disease. A literature review was initiated by the COST/Enter chILD working group aiming to describe published studies, to identify gaps in knowledge and to propose future research goals in regard to spirometry, whole-body plethysmography, infant and pre-school PFTs, measurement of diffusing capacity, multiple breath washout and cardiopulmonary exercise tests in chILD. The search revealed a limited number of papers published in the past three decades, of which the majority were descriptive and did not report pulmonary function as the main outcome.PFTs may be useful in different stages of management of children with suspected or confirmed chILD, but the chILD spectrum is diverse and includes a heterogeneous patient group in all ages. Research studies in well-defined patient cohorts are needed to establish which PFT and outcomes are most relevant for diagnosis, evaluation of disease severity and course, and monitoring individual conditions both for improvement in clinical care and as end-points in future randomised controlled trials.

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Section: Diffusing Capacity Measurementmentioning

confidence: 99%

Pulmonary function testing in children's interstitial lung disease

et al. 2020

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“…Furthermore, MS are expensive and bulky. Praca et al compared DLCO and Va measured by gas chromatography to values measured by MS, and they found that the former yielded results similar to the latter method. Their findings suggest that gas chromatography may be an alternative way to measure DLCO and Va in infants that is less expensive and cumbersome than MS.…”

Section: Introductionmentioning

confidence: 99%

Pediatric Pulmonology year in review 2018: Asthma, physiology/pulmonary function testing, and respiratory infections

Loughlin

Muston

et al. 2019

Pediatric Pulmonology

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Pediatric Pulmonology publishes original research, reviews, and case reports related to a wide range of children's respiratory disorders. In our “Year in Review” series, we summarize publications in our major topic areas from 2018, in the context of selected literature in these areas from other journals relevant to our discipline. This review covers selected articles on asthma, physiology/lung function testing, and respiratory infections.

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An alternative method to measure the diffusing capacity of the lung for carbon monoxide in infants

Abstract: Measuring DL and V at end-expiration using a gas chromatograph can provide an effective assessment of gas exchange in sleeping infants.

Cited by 2 publications

References 7 publications

Pulmonary function testing in children's interstitial lung disease

Pulmonary function testing in children's interstitial lung disease

Pediatric Pulmonology year in review 2018: Asthma, physiology/pulmonary function testing, and respiratory infections

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