Abstract:Objectives
Induced pluripotent stem cells (iPSCs) generated by monolayer cultures is plagued by low efficiencies, high levels of manipulation and operator unpredictability. We have developed a platform, reprogramming, expansion, and differentiation on Microcarriers, to solve these challenges.
Materials and Methods
Five sources of human somatic cells were reprogrammed, selected, expanded and differentiated in microcarriers suspension cultures.
Results
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