An All-in-One Highly Multiplexed Diagnostic Assay for Rapid, Sensitive, and Comprehensive Detection of Intraocular Pathogens

Bispo, Paulo J. M.; Belanger, Nicole L.; Li, Ashley; Liu, Renee; Susarla, Gayatri; Chan, Weilin; Chodosh, James; Gilmore, Michael S.; Sobrin, Lucia

doi:10.1016/j.ajo.2023.01.021

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2023

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“…It had PCR-level sensitivity, and quantification of DNA hybrids by NanoString had good correlations with the real-time PCR Ct values. Because it required nucleic acid extraction and the total time was approximately 12 h, it is not suitable for POCT [26].…”

Section: Ncounter ® Analysis Systemmentioning

confidence: 99%

Role of Recent PCR Tests for Infectious Ocular Diseases: From Laboratory-Based Studies to the Clinic

Sugita¹,

Takase

Nakano

2023

IJMS

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Infectious uveitis is a vision-threatening condition that requires prompt clinical diagnosis and proper treatment. However, rapid and proper diagnosis in infectious uveitis remains challenging. Several examination tests, including polymerase chain reaction (PCR) tests, are transitioning from laboratory-based basic research-level tests to bedside clinical tests, and recently tests have changed to where they can be performed right next to clinicians. In this review, we introduce an updated overview of recent studies that are representative of the current trends in clinical microbiological techniques including PCR tests for infectious uveitis.

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Section: Ncounter ® Analysis Systemmentioning

confidence: 99%