“…Complex soft tissue defects of the foot and ankle caused by trauma, infection, tumor cancer or diabetes are common and can be accompanied by exposed tendons, neurovascular bundles and bone. There are multiple options for the reconstruction of complex soft tissue defects in these areas, including the use of both pedicled flaps and free flaps (e.g., a lateral supramalleolar flap [2], a peroneal artery perforator flap [3,4], posterior tibial artery perforator flap [5], a sural neurocutaneous/neurofasciocutaneous flap [6,7,8], a medial pedis flap [9], a dorsal metatarsal flap [10], a dorsalis pedis flap [11], a pedicled or free medial plantar flap [12,13], a free groin flap [14,15], a free anterolateral thigh perforator flap [16,17,18], or a free anteromedial thigh perforator flap [19]). In addition, the successful reconstruction of complex soft tissue defects of the foot and ankle is critical because of the unique standing, weight-bearing and walking functions of the foot.…”