An Algorithm for Assessing Intraoperative Mean Arterial Pressure Lability 

Abstract

One potential application of expert systems to anesthesia practice is a "smart alarm" to detect blood pressure lability. It may also provide a better tool to assess the relation between lability and outcome than has been available previously.

L’aténolol ne modifierait pas les indicateurs de la profondeur de l’anesthésie chez les patients âgés — un réexamen des données

“…Absolute fractional changes between consecutive two-minute medians were calculated for all variables, as reported previously. 1,4 The intraoperative period was defined from surgical incision until closure of the surgical wound. For this period, percent frequency distribution for intraoperative BIS values was calculated for the following ranges: < 40, 40-50, 50-60, 60-70, 70-80, > 80.…”

Intraoperative arterial blood pressure lability is associated with improved 30 day survival

“…however, did not investigate associations of lability with outcome. 8 In the present study, we hypothesized that intraoperative haemodynamic lability is associated with an increase in 30 day mortality in patients undergoing non-cardiac surgery. As a secondary outcome, we looked at the incidence of non-fatal perioperative myocardial injury (PMI).…”

Computer control versus manual control of systemic hypertension during cardiac surgery

“…For postoperative cardiac surgical patients Chitwood et al (5) showed that more stable hemodynamics obtained by computer control significantly improve patient outcome by reducing blood loss, transfusion requirements and duration of stay on the intensive care unit. The effects of intraoperative hemodynamic stability on measures of patient outcome are less well defined, which might partly be explained by the fact that only recently have objective methods been proposed for qualifying hemodynamic stability during surgery (15). Systemic hypertension increases postoperative blood loss (16) and systemic hypertension, resulting from an increased systemic resistance, increases cardiac afterload and thus left ventricular stroke work.…”