“…There are three randomized clinical trials (RCTs), 17,39,41 one randomized trial with a crossover design, 44 one controlled study (not randomized), 15 one multiple baseline design, 16 five case series, 33,34,38,40,42,43 and three case reports. [35][36][37] Of the fourteen studies, two included more than 50 patients 15,41 and five included less than 10 patients. 16,[35][36][37]42 Nine studies did not include a control group.…”