An aggressive angiomyxoma of vulva - A rare entity - A case report

Das, Bishnu Prasad; Baruah, Dipankar; Medhi, Kaberee Bhuyan; Talukder, Bharat

doi:10.4103/0976-7800.191020

Cited by 6 publications

(5 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the ratio of occurrence in females to males is 6:1. 8 Aggressive angiomyxoma may be commonly misdiagnosed as angiomyofibroblastoma. However, the latter is well circumscribed, more cellular, and more vascular.…”

Section: Discussionmentioning

confidence: 99%

A giant aggressive angiomyxoma of the vulva in a dwarf: a rare case report

Mukherjee¹,

Prakash

Sodhiya³

et al. 2023

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Aggressive angiomyxoma is a rare soft tissue tumour that carries a high risk of local relapse. The tumour usually arises from the pelvic and perineal regions. We presented a case of a young girl with dwarfism, mental retardation and thyroid agenesis who presented with aggressive angiomyxoma of the vulva. As it is almost exclusively seen in women of reproductive age group, this is the first case reported in a teenage girl, to the best of our knowledge. A mentally retarded girl, aged fifteen years, presented with a large mass hanging from the vulva, with ulceration over the mass. She had short stature, anasarca, mental retardation, primary amenorrhoea, under-developed secondary sexual characters .and thyroid agenesis. Local examination revealed a pedunculated mass of 15 by 4 cm size arising from the mons pubis closely resembling a giant penis. Full hormonal and radiological work-up was done. Her condition was optimized and the mass was removed with wide excision of margins followed by cystoscopy under general anaesthesia. Histopathology and immunohistochemistry were suggestive of aggressive angiomyxoma. She has no recurrence till date. Despite its rarity, angiomyxoma should be considered in the differential diagnosis of any painless swelling located in the genitofemoral region. The principal treatment is surgical excision. Long term follow-up is needed due to its high tendency of local recurrence.

show abstract

Section: Discussionmentioning

confidence: 99%

A giant aggressive angiomyxoma of the vulva in a dwarf: a rare case report

Mukherjee¹,

Prakash

Sodhiya³

et al. 2023

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

show abstract

“…Occasionally, they are seen in male patients in related sites like the scrotum and inguinal region. However, the ratio of occurrence in females to males is 6:1 [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

Aggressive (deep) angiomyxoma of the vulva: a case report

et al. 2022

View full text Add to dashboard Cite

Background Aggressive angiomyxoma of the vulva is a benign, slow-growing tumor originating from myxoid cells of connective tissue. The tumor is known for multiple local recurrences with a low tendency to metastasize. Only around 350 cases have been documented in the scientific literature so far. Case presentation We report a case of a 40-year-old North Indian, unmarried woman with a swelling on the left labium majora for 7 years, along with surface ulceration over the mass. Local examination showed a well-circumscribed, 8 × 8 cm pedunculated mass arising from the left labium majora with an overlying ulcer measuring 6 cm × 4 cm. After taking informed written consent, wide local excision of the mass and surrounding margins was done under anesthesia. Histopathology was suggestive of aggressive angiomyxoma. Immunohistochemistry was done, which was positive for estrogen and progesterone receptors. Her postoperative recovery was uneventful. The patient was given three doses of gonadotropin-releasing hormone agonist (injection, leuprolide 3.75 mg) once a month. No recurrence has been reported so far on follow-up visits for 1 year. Conclusion Aggressive angiomyxoma is one of the differential diagnoses for vulvovaginal growth in a female. As the tumor is well known for local recurrences, correct diagnosis and appropriate management using a multidisciplinary approach are crucial to managing such patients.

show abstract

“…There are currently no guidelines for the postoperative follow-up. However, according to Das et al, patients should be followed for at least 15 years with yearly physical exams and potentially with MRI to rule out recurrence [9]. Some studies have shown benefit with preoperative treatment by radiation therapy or hormonal antagonists such as GnRH agonists in order to shrink the tumor to avoid extensive resection [1,2].…”

Section: Discussionmentioning

confidence: 99%

Histopathologic diagnosis of aggressive angiomyxoma following removal of an asymptomatic, stable vulvar mass

Megan¹,

Laura²,

Yuliya³

2020

IJCRIOG

View full text Add to dashboard Cite

Introduction: Aggressive angiomyxoma (AAM) is a rare, locally aggressive, benign tumor usually found in the female pelvis. Case Report: We present a 42-year-old Caucasian female undergoing removal of a non-enlarging, painless vulvar mass at time of hysteroscopic endometrial ablation for abnormal uterine bleeding. The patient had a past medical history notable for multiple malignant melanomas. Past surgical history included three low transverse cesarean sections, postpartum tubal ligation, and three wide excisions of melanomas. Family history was negative for dermatologic disease or cancers. The mass had been present for over two years; she desired removal for cosmetic purposes. At the time of surgery, the patient was asymptomatic and physical examination revealed a soft, mobile, approximately 2 cm, non-tender right labial mass. Previous ultrasound report described the mass as 2 × 2 cm and solid-appearing. During the surgery, a 5 × 2.6 × 1.4 cm irregular mass with soft, spongy contents was removed intact via incision followed by blunt and sharp dissection. Pathology of the specimen revealed AAM, with extension of tumor to the surgical margins. Histology and immunohistochemistry reports

show abstract

An aggressive angiomyxoma of vulva - A rare entity - A case report

Cited by 6 publications

References 13 publications

A giant aggressive angiomyxoma of the vulva in a dwarf: a rare case report

A giant aggressive angiomyxoma of the vulva in a dwarf: a rare case report

Aggressive (deep) angiomyxoma of the vulva: a case report

Histopathologic diagnosis of aggressive angiomyxoma following removal of an asymptomatic, stable vulvar mass

Contact Info

Product

Resources

About