An age-structured SIPC model of cervical cancer with immunotherapy
Eminugroho Ratna Sari,
Lina Aryati,
Fajar Adi-Kusumo
Abstract:<abstract><p>Immunotherapy is a targeted therapy that can be applied to cervical cancer patients to prevent DNA damage caused by human papillomavirus (HPV). The HPV infects normal cervical cells withing a specific cell age interval, i.e., between the $ G_1 $ to $ S $ phase of the cell cycle. In this study, we developed a new mathematical model of age-dependent immunotherapy for cervical cancer. The model is a four-dimensional first-order partial differential equation with time- and age-independent … Show more
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