An Advanced Lens Measurement Approach (ALMA) in post refractive surgery IOL power calculation with unknown preoperative parameters

Rosa, Nicola; Cione, Ferdinando; Pepe, Angela; Musto, Salvatore; Bernardo, Maddalena De

doi:10.1371/journal.pone.0237990

Cited by 33 publications

(28 citation statements)

References 51 publications

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“…The correlation between postoperative refraction error and AL and K has also been studied in patients that underwent cataract surgery after refractive surgery. Recently, an advanced lens measurement approach (ALMA) was proposed to improve the accuracy of postoperative refraction error by Rosa et al [ 23 ]. They showed the improvement of R Factor [ 24 ] and ALxK methods [ 25 ] by applying ALMA, which is a mixed theoretical regression method based on the SRK-T formula.…”

Section: Discussionmentioning

confidence: 99%

Conditional Process Analysis for Effective Lens Position According to Preoperative Axial Length

Yoo

Whang

2022

JCM

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Purpose: To predict the effective lens position (ELP) using conditional process analysis according to preoperative axial length. Setting: Yeouido St. Mary hospital. Design: A retrospective case series. Methods: This study included 621 eyes from 621 patients who underwent conventional cataract surgery at Yeouido St. Mary Hospital. Preoperative axial length (AL), mean corneal power (K), and anterior chamber depth (ACD) were measured by partial coherence interferometry. AL was used as an independent variable for the prediction of ELP, and 621 eyes were classified into four groups according to AL. Using conditional process analysis, we developed 24 structural equation models, with ACD and K acting as mediator, moderator or not included as variables, and investigated the model that best predicted ELP. Results: When AL was 23.0 mm or shorter, the predictability for ELP was highest when ACD and K acted as moderating variables (R2 = 0.217). When AL was between 23.0 mm and 24.5 mm or longer than 26.0 mm, the predictability was highest when K acted as a mediating variable and ACD acted as a moderating variable (R2 = 0.217 and R2 = 0.401). On the other hand, when AL ranged from 24.5 mm to 26.0 mm, the model with ACD as a mediating variable and K as a moderating variable was the most accurate (R2 = 0.220). Conclusions: The optimal structural equation model for ELP prediction in each group varied according to AL. Conditional process analysis can be an alternative to conventional multiple linear regression analysis in ELP prediction.

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Section: Discussionmentioning

confidence: 99%

Conditional Process Analysis for Effective Lens Position According to Preoperative Axial Length

Yoo

Whang

2022

JCM

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“…In the present study, a mean difference of about 20 microns between the two devices at the three different measurement points, with the limits of agreement in a range of about 35 microns, was found. Such differences in CT evaluation could be particularly significant in some clinical areas of ophthalmology, such as corneal refractive surgery [ 39 ], IOP measurement, and diagnosis and management of corneal disease [ 40 ], where a few microns could make a difference. For this reason, the two evaluated devices cannot be used interchangeably, unless the detected regression formulas are used, making them comparable.…”

Section: Discussionmentioning

confidence: 99%

Corneal thickness evaluation in healthy eyes: Comparison between two different Scheimpflug devices

et al. 2020

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Purpose To evaluate the correlation between corneal thickness (CT) measurements obtained with two Scheimpflug devices, Pentacam HR and Precisio, and to elaborate, if necessary, a regression formula which could make these results comparable. Design Retrospective, Comparative, Observational study. Setting Department of Medicine, Surgery and Dentistry, “Scuola Medica Salernitana” University of Salerno, Italy Methods One hundred twenty four healthy eyes of 124 volunteers (65 males; range: 20–32 years; mean age of 24.8 ± 1.7) were included in this study. CT was measured using Pentacam HR and Precisio in three different points: the pupil center (PC), the corneal apex (CA) and the thinnest point (TP). Results CT obtained with both devices at the PC, at the CA and at the TP showed a good correlation (r = 0.97, r = 0.97, r = 0.97, respectively), but Pentacam HR measurements were significantly thicker than those provided by Precisio (p < 0.01). The differences between Pentacam HR and Precisio were 21.9 ± 8.8 μm at the PC, 21.9 ± 8.9 μm at the CA, 19.1 ± 9.0 μm at the TP. The calculated regression formulas were: y = 0.9558x + 2.3196 for the PC, y = 0.9519x + 4.5626 for the CA, y = 0.9364x + 15.436 for the TP, where x is the CT measured with Pentacam HR and y is the Precisio measurement. Conclusions The findings provided by this study highlight that Precisio measures thinner corneas compared to Pentacam HR. The identified regression formulas could be utilized to make interchangeable the results obtained with these two devices.

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“…Subjects younger than 18 years of age or with systemic and ocular diseases, or patients who underwent other ophthalmic surgical procedures which could affect the eye [ 15 , 16 , 17 , 18 ], were excluded from this study.…”

Section: Methodsmentioning

confidence: 99%

Optical Coherence Tomography Analysis of Retinal Layers in Celiac Disease

Vitiello

Bernardo

Erra

et al. 2022

JCM

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Celiac disease is an immune-mediated, chronic, inflammatory, and systemic illness which could affect the eye. The aim of this study is to look for possible signs of retinal involvement in celiac disease that could be utilized as biomarkers for this disease. Sixty-six patients with celiac disease and sixty-six sex-matched healthy subjects were enrolled in this observational case–control study. A comprehensive ophthalmological evaluation, axial length measurements, and SD-OCT evaluation were performed. The thickness of the retinal layers at the circle centered on the fovea (1 mm in diameter) and the average of the foveal and parafoveal zones at 2 and 3 mm in diameter were evaluated, together with retinal volume and the peripapillary retinal nerve fiber layer (RNFL). Concerning the thicknesses of the retinal layers in each analyzed region, no statistically significant differences were found. The same results were obtained for the total volume. Regarding peripapillary RNFL, the celiac patients showed slightly thicker values than the healthy controls, except for temporal and nasal-inferior quadrants, with no statistically significant differences. All the analyzed parameters were similar for the celiac patients and the healthy individuals. This could be related either to the non-involvement of the retinal layers in celiac disease pathophysiology or to the gluten-free diet effect.

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An Advanced Lens Measurement Approach (ALMA) in post refractive surgery IOL power calculation with unknown preoperative parameters

Abstract: To test a new method to calculate the Intraocular Lens (IOL) power, that combines R Factor and ALxK methods, that we called Advance Lens Measurement Approach (ALMA).

Cited by 33 publications

References 51 publications

Conditional Process Analysis for Effective Lens Position According to Preoperative Axial Length

Conditional Process Analysis for Effective Lens Position According to Preoperative Axial Length

Corneal thickness evaluation in healthy eyes: Comparison between two different Scheimpflug devices

Optical Coherence Tomography Analysis of Retinal Layers in Celiac Disease

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