An Acylhydrazone-Based Fluorescent Sensor for Sequential Recognition of Al3+ and H2PO4−

Abstract

A novel acylhydrazone-based fluorescent sensor NATB was designed and synthesized for consecutive sensing of Al3+ and H2PO4−. NATB displayed fluorometric sensing to Al3+ and could sequentially detect H2PO4− by fluorescence quenching. The limits of detection for Al3+ and H2PO4− were determined to be 0.83 and 1.7 μM, respectively. The binding ratios of NATB to Al3+ and NATB-Al3+ to H2PO4− were found to be 1:1. The sequential recognition of Al3+ and H2PO4− by NATB could be repeated consecutively. In addition, the practicality of NATB was confirmed with the application of test strips. The sensing mechanisms of Al3+ and H2PO4− by NATB were investigated through fluorescence and UV–Visible spectroscopy, Job plot, ESI-MS, 1H NMR titration, and DFT calculations.

A Novel Coumarin‐Based Fluorescent Probe for Sequential Detection of Al3+ and H2PO4−

“…Dihydrogen phosphate (H 2 PO 4 − ) is biologically relevant anion which plays important role in genetic information storage, energy transduction, muscle contraction and signaling processing [4] . On the other hand, over‐use of phosphate can also lead to some side effect such as eutrophication or massive algal growth [5] . Therefore, an efficient method for detecting of Al 3+ and H 2 PO 4 − is full of significance [5–6] …”

“…[4] On the other hand, over-use of phosphate can also lead to some side effect such as eutrophication or massive algal growth. [5] Therefore, an efficient method for detecting of Al 3 + and H 2 PO 4 À is full of significance. [5][6] Among various methods for detection of ions, the fluorescence-based technology has received significant consideration due to its advantages of facile operation, high selectivity, low cost, easy visualization, quick response and bioimaging capability.…”

“…[5] Therefore, an efficient method for detecting of Al 3 + and H 2 PO 4 À is full of significance. [5][6] Among various methods for detection of ions, the fluorescence-based technology has received significant consideration due to its advantages of facile operation, high selectivity, low cost, easy visualization, quick response and bioimaging capability. [7] Although numerous single selective probes have been reported these years, multiple recognizition probes are still in highly demand.…”

“…[8] In view of the economic value and practical applications, these probes with multianalyte response for Al 3 + and H 2 PO 4 À are in highly desirable. Although two probes have been reported for the target these years, [5,9] but the probes still need to be improved.…”

Selective fluorescent detection of Zn2+ by a rhodanine‐based chemosensor

“…[13][14][15] Analytical tools were developed to detect zinc ions like atomic absorption spectrometry (AAS), flame atomic absorption spectrometry, graphite furnace atomic absorption spectrometry (GFAAS), and inductively coupled plasma atomic emission spectroscopy (ICP-AES). [16][17][18][19] However, the methods demand costly instruments, complicated preparation procedures, and skillful experts. [20,21] Recently, fluorescent methods have gained much attention because they take some advantages that involve simple preparation and operation and low cost.…”