“…Given evidence for prefrontal control over posterior negativity amplitudes, these data might indicate a task-driven “sharpening” of visual processing (Rustamov et al, 2014 ), putatively in the service of functional compensation (Reuter-Lorenz and Cappell, 2008 ) and probably through additional mechanisms recruited in frontoparietal attention networks (Ptak, 2012 ; Vossel et al, 2014 ). If so, the present posterior negativity finding is in line with multiple neuroimaging studies that used various paradigms, and that demonstrated a diversity of patterns of enhanced cortical activity in ALS patients (Kew et al, 1993b ; Schoenfeld et al, 2005 ; Han and Ma, 2006 ; Stanton et al, 2006 ; Lulé et al, 2007 ; Dounaud et al, 2011 ; Goldstein et al, 2011 ; Mohammadi et al, 2011 , 2015 ; Cosottini et al, 2012 ; Witiuk et al, 2014 ; see Turner et al, 2012 , for review).…”