“…Other recurrent abnormalities have been described, including structural aberrations of chromosomes 1, 3, 6, 11, 16 and X, loss of chromosome 22 and gains of chromosomes 6 and 8 (Farwell et al, 1977;Bigner et al, 1988Bigner et al, , 1990Griffin et al, 1988;Callen et al, 1989;Karnes et al, 1992;Neumann et al, 1993;Fujii et al, 1994). Few gene amplifications have been reported, involving MYC, MYCN or EGFR (Rouah et al, 1989;Wasson et al, 1990;Fuller and Bigner, 1992;Badiali et al, 1995), and more recently the 5p15 and 11q22 chromosomal regions (Reardon et al, 1997).…”