Amphiphilic Polymers Based on Poly(2‐oxazoline)s – From ABC‐Triblock Copolymers to Micellar Catalysis

Abstract

In this presentation we give an overview on our results in the field of poly(2‐oxazolines). By means of living cationic polymerization in combination with the initiation and termination method, functionalized poly(2‐oxazoline)s have been prepared, that were used as (i) macromonomers to form graft copolymers, (ii) lipopolymers to prepare stealth liposomes, (iii) ABC like polymers to form two compartment micellar networks and (iv) macroligand for micellar catalysis application. Within this report, we will discuss in detail the synthesis and characterization of various poly(2‐oxazoline)s for the above mentioned research areas.

Poly(2‐oxazoline)s based on fatty acids

“…Amphiphilic poly(2-oxazoline) block copolymers comprising a poly(NonOx) block were developed for micellar catalysis by Nuyken and Weberskirch [59,60]. Therefore, block copolymers consisting of a hydrophilic poly(MeOx) block and a hydrophobic block consisting of NonOx and a catalyst-functionalized monomer were prepared and subsequently used as micellar catalysts in aqueous media.…”

Star poly(2‐ethyl‐2‐oxazoline)s—synthesis and thermosensitivity

“…A hyperbranched core was prepared by melt condensation polymerization of 4,4‐bis(4‐hydroxyphenyl)valeric acid, followed by reaction with 3‐(chloromethyl)benzoyl chloride. The polymerization of 2‐methyl‐2‐oxazoline from this core using KI or CF 3 SO 3 Ag as the counterion exchange agent provided star molecules with up to 12 grafted arms 31, 32. Recently Banerjee et al 33 reported the synthesis of hyperbranched poly(ethylene glycol)‐like cores that were grafted with polyethyleneimine arms; these structures were formed by hydrolyzing the poly(2‐alkyl‐2‐oxazoline) arms.…”

Bioinspired Block Copolymers: Translating Structural Features from Proteins to Synthetic Polymers

“…In fact, hydrophobic domains can be nanostructured when fluorocarbon building blocks are employed, [8,22,[24][25][26] due to the mutual poor compatibility of fluorocarbons and most hydrocarbon derivatives. Though singular impressive examples have been reported most recently, [22,[27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44] and some theoretical consideration has been given to the topic [45][46][47][48][49][50][51] the number of suited block polymers is still marginal. In fact, the synthesis of ternary amphiphilic block copolymers is far from trivial, in particular of such containing fluorocarbon blocks, e.g., due to difficulties in finding an inert common good solvent for all blocks.…”