Amphetamine abuse and acute thrombosis of left circumflex coronary artery

Cardiovascular complications among individuals with amphetamine-positive urine drug screening admitted to a tertiary care hospital in Riyadh

“…The CV complications were predominantly due to coronary artery disease and mostly in form of ACS/MI ( n = 31, 74%) out of which ST-elevation MI was present in 20 cases (48%). Association between ATS use and ACS/MI has been reported in several studies and case reports [13], [23]. Risk factors for coronary artery disease in this population included being male (100%), diabetes mellitus (27.5%), and smoking (at least 60%), which more or less reflect the usual local population risk factor profile.…”

Cardiovascular Complications of Acute Amphetamine Abuse: Cross-sectional study

“…[19][20][21][22] In a case report, Khattab et al described a 54-year-old man with chest pains after amphetamine use, increased troponin I and CK-MB levels and complete obstruction of the left circumflex coronary artery due to acute thrombosis. 23 The most commonly observed abnormal ECG findings in the current study were sinus tachycardia (43.0%) and sinus tachycardia plus a prolonged QT interval (34.3%). Haning et al observed prolonged QT intervals among 27.2% of patients abusing methamphetamines in the USA.…”

Acute myocardial infarction with multiple coronary thromboses in a young addict of amphetamines and benzodiazepines

“…Moreover, diagnosis of STEMI among amphetamine users with simultaneous thrombosis of the LCX and the RCA has not been reported previously. By contrast, cases with abnormalities in the LAD artery [9], [11], RCA [6], [11], or LCX alone [12] due to amphetamine use have been reported. Also interesting in our case is the persistent thrombosis despite aggressive anticoagulation.…”