Amperometric Method for Detecting Paracetamol using a Carbon Paste Electrode Modified with Vanadium(V) Oxide

Abstract

This new and simple amperometric method takes advantage of the electroactivity of V2O5 in the oxidation of paracetamol (PCM) on a carbon paste electrode (CPE). With the modified electrode (VOX/CPE) the anode peak current for PCM was more than 100 % than that of the unmodified electrode. The electrode surface was characterized by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM). The amperograms were measured at +0.70 V (vs Ag/AgCl), and the calibration curve indicated a detection limit of 0.06 μmol/L and a sensitivity of 1.93 μA/μM cm2. The modified electrode was used in the detection of solid drugs such as PCM tablets and children's syrup with acceptable results.

Electrochemical Determination of Uric Acid Using a Nanocomposite Electrode with Molybdenum Disulfide/Multiwalled Carbon Nanotubes (MoS2@MWCNT)

“…There are very few reports on the studied electrodes modified with MoS 2 and MWCNTs in the presence of Fe(CN) 6 3+/4+ that have calculated the active area value. In relation to the value calculated in this paper, the active area value is much smaller compared to other larger-diameter electrodes, in which the reproduced active area is normally greater than 0.10 cm 2 in electrodes modified with metal cation oxides and nanoparticles [ 26 ].…”