Amperometric Lactate Biosensor Based on Carbon Paste Electrode Modified with Benzo[<i>c</i>]cinnoline and Multiwalled Carbon Nanotubes

Çelik, Ali; Öztürk, Funda; Erden, Pınar Esra; Kaçar, Ceren; Kılıç, Esma

doi:10.1002/elan.201500180

Cited by 11 publications

(5 citation statements)

References 53 publications

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“…Öztürk et al [ 116 ] reported an amperometric lactate biosensor based on a carbon paste electrode modified with benzo[c]cinnoline and multiwalled carbon nanotubes. Its characteristics showed, that it can be used for determination of lactate in human serum.…”

Section: Cyclic and Macrocyclic Derivatives Of Azobenzene(s)mentioning

confidence: 99%

Azo group(s) in selected macrocyclic compounds

Wagner‐Wysiecka

Łukasik

Biernat

et al. 2018

J Incl Phenom Macrocycl Chem

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Azobenzene derivatives due to their photo- and electroactive properties are an important group of compounds finding applications in diverse fields. Due to the possibility of controlling the trans–cis isomerization, azo-bearing structures are ideal building blocks for development of e.g. nanomaterials, smart polymers, molecular containers, photoswitches, and sensors. Important role play also macrocyclic compounds well known for their interesting binding properties. In this article selected macrocyclic compounds bearing azo group(s) are comprehensively described. Here, the relationship between compounds’ structure and their properties (as e.g. ability to guest complexation, supramolecular structure formation, switching and motion) is reviewed.

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Section: Cyclic and Macrocyclic Derivatives Of Azobenzene(s)mentioning

confidence: 99%

Azo group(s) in selected macrocyclic compounds

Wagner‐Wysiecka

Łukasik

Biernat

et al. 2018

J Incl Phenom Macrocycl Chem

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show abstract

“…They also exhibit excellent sensitivity and reproducibility. Their performance can be greatly improved by incorporating nanomaterials such as gold, copper [15], platinum [16,17], Prussian blue or zinc nanoparticles [18], carbon nanodots [19], quantum dots [20], magnetic beads [21][22][23][24], graphene [25,26], graphene oxide [27][28][29][30], and carbon nanotubes [15,27,31]. The large surface area afforded by nanomaterials facilitates the capture of the target at the electrode/solution interface and increases currents.…”

Section: Biosensor Configurationmentioning

confidence: 99%

Micro- and nanosensors for detecting blood pathogens and biomarkers at different points of sepsis care

et al. 2022

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Severe infections can cause a dysregulated response leading to organ dysfunction known as sepsis. Sepsis can be lethal if not identified and treated right away. This requires measuring biomarkers and pathogens rapidly at the different points where sepsis care is provided. Current commercial approaches for sepsis diagnosis are not fast, sensitive, and/or specific enough for meeting this medical challenge. In this article, we review recent advances in the development of diagnostic tools for sepsis management based on micro- and nanostructured materials. We start with a brief introduction to the most popular biomarkers for sepsis diagnosis (lactate, procalcitonin, cytokines, C-reactive protein, and other emerging protein and non-protein biomarkers including miRNAs and cell-based assays) and methods for detecting bacteremia. We then highlight the role of nano- and microstructured materials in developing biosensors for detecting them taking into consideration the particular needs of every point of sepsis care (e.g., ultrafast detection of multiple protein biomarkers for diagnosing in triage , emergency room, ward, and intensive care unit; quantitative detection to de-escalate treatment; ultrasensitive and culture-independent detection of blood pathogens for personalized antimicrobial therapies; robust, portable, and web-connected biomarker tests outside the hospital). We conclude with an overview of the most utilized nano- and microstructured materials used thus far for solving issues related to sepsis diagnosis and point to new challenges for future development. Graphical abstract Supplementary Information The online version contains supplementary material available at 10.1007/s00604-022-05171-2.

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“…In this case, a percent relative response, which refers to the signal of the initial day retained after being stored, was used to monitor the remaining signal response of the nanocomposite and the modified electrode after the storage time to evaluate the shelf-life of the biosensor. 25,26 The nanocomposite was stored in a brown glass bottle and the modified electrode was kept in a desiccator at room temperature when not in use. Under the storage conditions, the nanocomposite exhibited good stability.…”

Section: Reproducibility and Stabilitymentioning

confidence: 99%