Amperometric detection of benzoyl peroxide in pharmaceutical preparations using carbon paste electrodes with peroxidases naturally immobilized on coconut fibers☆

Kozan, J.V.B.; Silva, R.P.; Serrano, Sı́lvia Helena Pires; Lima, Antonio William Oliveira; Angnes, Lúcio

doi:10.1016/j.bios.2009.09.044

Cited by 32 publications

(19 citation statements)

References 20 publications

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“…In 2011, seven departments including ministry of health officially announced that BPO is prohibited to add into flour in China. So far, the analytical methods for BPO in flour mainly include spectroscopy, chromatography, mass spectrometry and electrochemical method2324252627. RRS, using synchronous scanning technology by common fluorescence spectrometer, has the characteristics of simple and sensitive, and was used in biochemical analysis combining with nanogold or nanosilver7282930.…”

mentioning

confidence: 99%

A new silver nanorod SPR probe for detection of trace benzoyl peroxide

Jiang

Wen

Luo

et al. 2014

Sci Rep

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The stable silver nanorod (AgNR) sol in red was prepared by the two-step procedure of NaBH4-H2O2 and citrate heating reduction. The AgNR had a transverse and a longitudinal surface plasmon resonance (SPR) absorption peak at 338 nm and 480 nm. Meanwhile, two transverse and longitudinal SPR Rayleigh scattering (SPR-RS) peaks at 340 nm and 500 nm were observed firstly using common fluorescence spectrometer. The SPR absorption, RS, surface enhanced Raman scattering (SERS) and electron microscope technology were used to study the formation mechanism of red silver nanorods and the SERS enhancement mechanism of nano-aggregation. The AgNR-BPO SPR absorption and AgNR-NaCl-BPO SPR-RS analytical systems were studied to develop two new simple, rapid, and low-cost SPR methods for the detection of trace BPO.

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confidence: 99%

A new silver nanorod SPR probe for detection of trace benzoyl peroxide

Jiang

Wen

Luo

et al. 2014

Sci Rep

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“…Moreover, several reports evidenced the correlation between PPO activity, protein content and analytic signal in biosensor development, and associated the better phenolic probe detection to PPO-mediated oxidation of phenolic moieties followed by electrochemical reduction of ketone residues, as showcased in Figure 1. [9][10]24,25 In view of these findings, the biosensor produced from immature fruits (i.e. Lob.EE) was selected for further optimization steps.…”

Section: Biosensor Development and Optimizationmentioning

confidence: 96%

Development and Optimization of Solanum Lycocarpum Polyphenol Oxidase-Based Biosensor and Application towards Paracetamol Detection

et al. 2020

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Purpose: The development biosensing technologies capable of delivering fast and reliable analysis is a growing trend in drug quality control. Considering the emerging use of plant-based polyphenol oxidases (PPO) as biological component of electrochemical biosensors, this work reports the first Solanum lycocarpum PPO biosensor and its use in the pharmaceutical analysis of paracetamol in tablet formulations. Methods: The biosensor was optimized regarding fruit maturation (immature and mature-ripe), vegetal extract volume to be used in biosensor construction as well as optimal pH of electrochemical cell fluid. Results: Results evidenced that the extract which rendered the biosensor with best analytical performance was from immature fruits, and the biosensor produced using 100 µL of crude plant extract promoted better faradaic signal gathering. Moreover, when neutral pH media was used in the electrochemical cell, the biosensor showcased best faradaic signal output from the used redox probe (catechol), suggesting thence that the method presents high sensibility for phenolic compounds detection. Furthermore, the biosensor was able to quantify paracetamol in a linear range from 50 to 300 μM, showcasing LoD and LoQ of 3 μM and 10 μM, respectively. Conclusion: after careful evaluation, this biosensor might be a low-cost alternative for conventional pharmaceutical quality control methods.

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“…BPO could be absorbed into the skin resulting in allergic reactions and its decomposition products, which are difficult to metabolize, usually trigger tissue damage and disease [7,8]. Worse still, BPO is a potential tumor inducer and could cause DNA damage, lipid peroxidation, and thiol oxidation due to its genotoxic effects on human peripheral lymphocytes [9,10]. Considering its potential hazards, reliable BPO analytical methods with high efficiency and accuracy will facilitate the understanding and utilization of BPO, and guiding the clinic treatment.…”

Section: Introductionmentioning

confidence: 99%

“…In recent years, a series of analytical methods for BPO detection, including chromatographic method [11], electrochemistry [9], capillary electrophoresis [2], Raman hyperspectral detection [12,13], and flow injection analysis [14] have appeared in succession. Although these methods are highly specific and sensitive for BPO detection, they still suffer from many problems such as tedious sample pre-treatment, large solvent consumption, expensive instrumentation, and professional operation [15].…”

Section: Introductionmentioning

confidence: 99%

Highly Sensitive Detection of Benzoyl Peroxide Based on Organoboron Fluorescent Conjugated Polymers

Yin

Zhang

et al. 2019

Polymers

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The method capable of rapid and sensitive detection of benzoyl peroxide (BPO) is necessary and receiving increasing attention. In consideration of the vast signal amplification of fluorescent conjugated polymers (FCPs) for high sensitivity detection and the potential applications of boron-containing materials in the emerging sensing fields, the organoboron FCPs, poly (3-aminophenyl boronic acid) (PABA) is directly synthesized via free-radical polymerization reaction by using the commercially available 3-aminophenyl boronic acid (ABA) as the functional monomer and ammonium persulfate as the initiator. PABA is employed as a fluorescence sensor for sensing of trace BPO based on the formation of charge-transfer complexes between PABA and BPO. The fluorescence emission intensity of PABA demonstrates a negative correlation with the concentration of BPO. And a linear range of 8.26 × 10−9 M–8.26 × 10–4 M and a limit of detection of 1.06 × 10–9 M as well as a good recovery (86.25%–111.38%) of BPO in spiked real samples (wheat flour and antimicrobial agent) are obtained. The proposed sensor provides a promising prospective candidate for the rapid detection and surveillance of BPO.

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Amperometric detection of benzoyl peroxide in pharmaceutical preparations using carbon paste electrodes with peroxidases naturally immobilized on coconut fibers☆

Cited by 32 publications

References 20 publications

A new silver nanorod SPR probe for detection of trace benzoyl peroxide

A new silver nanorod SPR probe for detection of trace benzoyl peroxide

Development and Optimization of Solanum Lycocarpum Polyphenol Oxidase-Based Biosensor and Application towards Paracetamol Detection

Highly Sensitive Detection of Benzoyl Peroxide Based on Organoboron Fluorescent Conjugated Polymers

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