AMPATH-Oncology: A model for comprehensive cancer care in sub-Saharan Africa

Strother, Robert Matthew; Asirwa, Fredrick Chite; Busakhala, Naftali; Njiru, Evangeline; Orang’o, Elkanah Omenge; Njuguna, Festus; Carter, J.; Mega, Anthony; Mostert, Saskia; Kaspers, Gertjan J. L.; Rosen, Barry P.; Krzyzanowska, M. K.; Washington, Sierra; Skiles, Jodi; Griest, A.; Rosmarin, Alan G.; Loehrer, Patrick J.

doi:10.1016/j.jcpo.2013.06.002

Cited by 41 publications

(37 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As outcomes for patients with communicable disease such as HIV improved, chronic diseases, such as cancer, have emerged as the second health wave crisis. 15,16 The growth of AMPATH Oncology was initially hampered by available resources and clinical demands from adult and pediatric oncology. AM-PATH Oncology transitioned eventually into care for AIDS-related malignancies and then to broader-based cancer treatment services.…”

Section: The Western Kenyan Experience: Care Leads the Waymentioning

confidence: 99%

Medical Education and Training: Building In-Country Capacity at All Levels

Asirwa

Greist

Busakhala

et al. 2016

JCO

View full text Add to dashboard Cite

Poorly trained workers and limited workforce capacity contribute immensely to barriers in cancer control in low- and middle-income countries (LMICs). Because of an increasing disease burden and the gap in trained personnel, it is critical that LMICs must develop appropriate in-country training programs at all levels to adequately address their cancer-related outcomes. The training in LMICs of cancer health personnel should address priority cancer diseases in the specific country by developing caregivers, trainers, researchers, and administrators at all levels of health care and all cadres of staff, from the community level to the national level. The Academic Model of Providing Access to Health care is a representative model of how a public tertiary hospital like the Moi Teaching and Referral Hospital in an LMIC setting can leverage its resources, collaborate with partners from high-resource countries, and assist in the development of a training center to spearhead a sustainable education program.

show abstract

Section: The Western Kenyan Experience: Care Leads the Waymentioning

confidence: 99%

Medical Education and Training: Building In-Country Capacity at All Levels

Asirwa

Greist

Busakhala

et al. 2016

JCO

View full text Add to dashboard Cite

show abstract

“…Each of these layers of service delivery is elaborate, and, although more research is needed, there are a number of important articles delineating the process of overcoming such challenges in resourceconstrained settings. [6][7][8][9][10][11][12][13][14] When making decisions about establishing or strengthening a national cancer program, policy makers must have knowledge of the number of patients with each disease seen in their country and which types of cancer can be affected. This analysis can be time consuming, and a disease-based decision-making platform is one way that countries have prioritized medicines for procurement when resources are limited.…”

Section: Introductionmentioning

confidence: 99%

Proposing Essential Medicines to Treat Cancer: Methodologies, Processes, and Outcomes

Shulman

Wagner

Barr

et al. 2016

JCO

View full text Add to dashboard Cite

Purpose A great proportion of the world's cancer burden resides in low- and middle-income countries where cancer care infrastructure is often weak or absent. Although treatment of cancer is multidisciplinary, involving surgery, radiation, systemic therapies, pathology, radiology, and other specialties, selection of medicines that have impact and are affordable has been particularly challenging in resource-constrained settings. In 2014, at the invitation of the WHO, the Union for International Cancer Control convened experts to develop an approach to propose essential cancer medicines to be included in the WHO Model Essential Medicines Lists (EML) for Adults and for Children, as well as a resulting new list of cancer medicines. Methods Experts identified 29 cancer types with potential for maximal treatment impact, on the basis of incidence and benefit of systemic therapies. More than 90 oncology experts from all continents drafted and reviewed disease-based documents outlining epidemiology, diagnostic needs, treatment options, and benefits and toxicities. Results Briefing documents were created for each disease, along with associated standard treatment regimens, resulting in a list of 52 cancer medicines. A comprehensive application was submitted as a revision to the existing cancer medicines on the WHO Model Lists. In May 2015, the WHO announced the addition of 16 medicines to the Adult EML and nine medicines to the Children's EML. Conclusion The list of medications proposed, and the ability to link each recommended medicine to specific diseases, should allow public officials to apply resources most effectively in developing and supporting nascent or growing cancer treatment programs.

show abstract

“…These interactions are designed to include education, mentoring and funding (Strother et al, 2013;Israels et al, 2015). Such arrangements make it easier for modifications to be made to treatment guidelines, making use of available local facilities and expertise that can subsequently be built on.…”

Section: Resultsmentioning

confidence: 99%

Guidelines in lower‐middle income countries

2017

View full text Add to dashboard Cite

Summary Guidelines include recommendations intended to optimize patient care; used appropriately, they make healthcare consistent and efficient. In most lower‐middle income countries (LMICs), there is a paucity of well‐designed guidelines; as a result, healthcare workers depend on guidelines developed in Higher Income Countries (HICs). However, local guidelines are more likely to be implemented because they are applicable to the specific environment; and consider factors such as availability of resources, specialized skills and local culture. If guidelines developed in HICs are to be implemented in LMICs, developers need to incorporate local experts in their development. Involvement of local stakeholders may improve the rates of implementation by identifying and removing barriers to implementation in LMICs. Another option is to encourage local experts to adapt them for use in LMICs; these guidelines may recommend strategies different from those used in HICs, but will be aimed at achieving the best practicable standard of care. Infrastructural deficits in LMICs could be improved by learning from and building on the successful response to the human immunodeficiency virus/acquired immunodeficiency syndrome pandemic through interactions between HICs and LMICs. Similarly, collaborations between postgraduate medical colleges in both HICs and LMICs may help specialist doctors training in LMICs develop skills required for guideline development and implementation.

show abstract

AMPATH-Oncology: A model for comprehensive cancer care in sub-Saharan Africa

Cited by 41 publications

References 46 publications

Medical Education and Training: Building In-Country Capacity at All Levels

Medical Education and Training: Building In-Country Capacity at All Levels

Proposing Essential Medicines to Treat Cancer: Methodologies, Processes, and Outcomes

Guidelines in lower‐middle income countries

Contact Info

Product

Resources

About