<i>Schistosoma mansoni</i> Infection: A Major Contributor of Reduced Effective T Helper Responses against <i>Plasmodium falciparum</i> and <i>Schistosoma mansoni</i> Co-Infection in <i>ex vivo</i>: A Cross-Sectional Study to Assess Th1, Th2 & Th17 Immune Responses
Abstract:Background: Parasitic worms evade immune responses, and interactions between diseases can cause altered immunologic outcomes compared to what usually occurs with single infections. These interactions may influence vaccine and chemotherapeutic efficacy. Schistosoma mansoni and Plasmodium falciparum are co-endemic in Uganda and are the leading parasitic causes of public health problems across sub-Saharan Africa. Objectives: The overall aim was therefore, to elucidate the impact of S. mansoni infection on protect… Show more
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