Amorphous carbon nanoparticles: a versatile label for rapid diagnostic (immuno)assays

Posthuma-Trumpie, Geertruida A.; Wichers, J.H.; Koets, Marjo; Berendsen, L.B.J.M.; Amerongen, A. van

doi:10.1007/s00216-011-5340-5

Cited by 140 publications

(72 citation statements)

References 52 publications

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“…These characteristics show that CB has the ability to intercalate ions on graphite layers [29], which affects electrical conduction between particles by tunneling [30] and the surface reaction. In particular, the surface area, the number of edges planned, and the structural defects depend on the synthesis or functionalization processes, which create several functional groups that can be useful for the immobilization of various species, such as enzymes [31], genetic material [32], antibodies [33], and nanoparticles [4]. The sum of structural and electrical/electronic characteristics, ability to produce stable dispersion without the need for sophisticated procedures, and the fact that it is an extremely cheap material make the CB an interesting nanostructured material for the development of electrochemical devices for sensing and biosensing.…”

Section: Considerations On Carbon Black Nanomaterialsmentioning

confidence: 99%

Electrochemical Biosensors Based on Nanostructured Carbon Black: A Review

Silva

Moraes

Janegitz

et al. 2017

Journal of Nanomaterials

129

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Carbon black (CB) is a nanostructured material widely used in several industrial processes. This nanomaterial features a set of remarkable properties including high surface area, high thermal and electrical conductivity, and very low cost. Several studies have explored the applicability of CB in electrochemical fields. Recent data showed that modified electrodes based on CB present fast charge transfer and high electroactive surface area, comparable to carbon nanotubes and graphene. These characteristics make CB a promising candidate for the design of electrochemical sensors and biosensors. In this review, we highlight recent advances in the use of CB as a template for biosensing. As will be seen, we discuss the main biosensing strategies adopted for enzymatic catalysis for several target analytes, such as glucose, hydrogen peroxide, and environmental contaminants. Recent applications of CB on DNA-based biosensors are also described. Finally, future challenges and trends of CB use in bioanalytical chemistry are discussed.

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Section: Considerations On Carbon Black Nanomaterialsmentioning

confidence: 99%

Electrochemical Biosensors Based on Nanostructured Carbon Black: A Review

Silva

Moraes

Janegitz

et al. 2017

Journal of Nanomaterials

129

View full text Add to dashboard Cite

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“…21,120 However, there are few reports of their application in the cellular delivery of therapeutic agents. One recent report on this subject describes the use of hollow permeable carbon nanospheres (several hundred nanometers in size) that are coated in biodegradable polymer for the oral delivery of insulin.…”

Section: Porous Carbon Nanospheres For Drug Deliverymentioning

confidence: 99%

“…19,20 There are already many reports that discuss the properties and biomedical applications of carbon nanotubes, graphene and even amorphous carbon nanoparticles. [21][22][23][24] In this review, we focus on the therapeutic applications (nanomedicine and drug delivery) of spherical nanocarbon materials, mainly fullerene nanoparticles, carbon nanohorn aggregates, nanodiamonds and porous carbon nanospheres (Figure 1). These nanocarbon materials have distinct structures, comprising SP 2 or SP 3 hybridized carbons.…”

Section: Introductionmentioning

confidence: 99%

Therapeutic applications of low-toxicity spherical nanocarbon materials

Wang

et al. 2014

NPG Asia Mater

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Nanocarbon materials have received considerable attention due to their unique structure and properties, which make them promising candidate materials for use in biomedical applications. In this review, we discuss the therapeutic applications of spherical nanocarbon materials, including fullerene nanoparticles, carbon nanohorn aggregates, nanodiamonds and porous carbon nanospheres, and their toxicology in biological systems. We put special emphasis on the antitumor effects of these multifunctional nanoparticles, which operate via novel mechanisms in a highly efficient manner. The low toxicities of these spherical nanocarbon materials as well as the possible effects of shape on toxicity are discussed.

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“…Carbon nanoparticles have been used as an alternative labeling tag because of their high sensitivity, low cost, high stability, and ease of preparation (Posthuma-Trumpie et al, 2012). Noguera et al (2011) developed a carbon nanoparticle-based LFTS for the detection of Shiga toxin-producing E. coli.…”

Section: Labeling Tagsmentioning

confidence: 99%

A Review on Lateral Flow Test Strip for Food Safety

Kim¹,

Lim²,

Mo³

2015

Journal of Biosystems Engineering

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Background: Foodborne disease outbreaks from various food sources are a major health concern worldwide. Current methods for detection of foodborne pathogens are both expensive and time-consuming. Purpose: This review aims to present the current information available on the use of lateral flow test strips to detect pathogens in food products to enhance food safety. Results: Frequent foodborne disease outbreaks from various food sources have increased the need for rapid and easy methods for routine analysis of foodborne pathogens. Present detection methods for foodborne pathogens require expensive instruments, experts, and long time for sample analysis. Lateral flow test strips have drawn attention in recent years because of their ability to detect analytes quickly and easily. This review focuses on the principle of the lateral flow test, the various formats of lateral flow test strips, recognition elements, labeling tags, and reading instruments. In addition, this review also discusses the future prospects for the lateral flow test strips.

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Amorphous carbon nanoparticles: a versatile label for rapid diagnostic (immuno)assays

Cited by 140 publications

References 52 publications

Electrochemical Biosensors Based on Nanostructured Carbon Black: A Review

Electrochemical Biosensors Based on Nanostructured Carbon Black: A Review

Therapeutic applications of low-toxicity spherical nanocarbon materials

A Review on Lateral Flow Test Strip for Food Safety

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