Among older adults, the responsiveness of self-rated health to changes in Charlson comorbidity was moderated by age and baseline comorbidity

Charlson comorbidity score is a strong predictor of mortality in hemodialysis patients

“…The CCI has been used to assess the survival of patients with a variety of disease states [6, 30–33]. CCI has also been used to measure comorbidity in ESRD patients [3, 9].…”

“…Older patients may or may not adapt to their preexisting illness and appear less likely to further reduce their health perceptions in case their comorbid conditions aggravate [30]. A study showed that increase in age was associated with better mental health component but poorer physical component of health-related quality of life in patients suffering from chronic diseases [35].…”

Among nonagenarians, congruence between self-rated and proxy-rated health was low but both predicted mortality

“…A plausible explanation can be found in the adaptation process and decreasing aspiration levels [28]. A recent study demonstrated the role of adaptation in health assessments: in response to new chronic conditions, older individuals with greater pre-existing co-morbidity were less likely to further decrease their health assessments than younger, healthier individuals [29]. Studies also show that the aspiration level regarding health decreases with advancing age, and the requirements for good health become more modest [30].…”

Correlates of Subjective Health Across the Aging Lifespan

“…Metaanalysis (of 176 effect sizes for physical illness and 118 effect sizes for functional limitations) found larger associations in those aged 60 to 75 years compared to those aged above 75 (Pinquart, 2001), and a very large data linkage study of older Americans found a decreasing relationship between SRH and number of comorbid conditions with advancing age (Heller, Ahern, Pringle, & Brown, 2009). Metaanalysis (of 176 effect sizes for physical illness and 118 effect sizes for functional limitations) found larger associations in those aged 60 to 75 years compared to those aged above 75 (Pinquart, 2001), and a very large data linkage study of older Americans found a decreasing relationship between SRH and number of comorbid conditions with advancing age (Heller, Ahern, Pringle, & Brown, 2009).…”