Amniotic Membrane Transplantation for Symptomatic Conjunctivochalasis Refractory to Medical Treatments

Meller, Daniel; Maskin, Steven L.; Pires, Renato T. F.; Tseng, Scheffer C.G.

doi:10.1097/00003226-200011000-00008

Cited by 77 publications

(45 citation statements)

References 23 publications

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“…2,[6][7][8][9]13,14,[29][30][31] However, most of these techniques only focus on the removal of the redundant conjunctiva itself. In contrast, and in our hypothesis, conjunctivochalasis is regarded as the most important cause to initiate tear meniscus dysfunction.…”

Section: Discussionmentioning

confidence: 99%

Clinical Impact of Conjunctivochalasis on the Ocular Surface

Yokoi

Komuro

Nishii

et al. 2005

Cornea

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Section: Discussionmentioning

confidence: 99%

Clinical Impact of Conjunctivochalasis on the Ocular Surface

Yokoi

Komuro

Nishii

et al. 2005

Cornea

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“…Tiende a ser bilateral, de localización inferior y es más frecuente en edad avanzada (1,2). Las formas leves causan un agravamiento de la sequedad ocular preexistente con una película lagrimal inestable y retraso en el aclaramiento de fluoresceína.…”

Section: Introductionunclassified

Injerto de membrana amniótica con adhesivo tisular en el tratamiento de la conjuntivocalasia refractiva

Fernández-Hortelano

Moreno-Montañés

Heras-Mulero

et al. 2007

Arch Soc Esp Oftalmol

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RESUMENCaso clínico: Paciente de 63 años que presenta una conjuntivocalasia bilateral con lagrimeo, picor, escozor y retraso en el aclaramiento de fluoresceí-na. Al no observarse mejoría sintomática con el tratamiento tópico, se interviene quirúrgicamente con implante de membrana amniótica sin sutura. Discusión: La conjuntivocalasia es una patología frecuente con síntomas comunes a la sequedad ocular. Cuando no hay respuesta al tratamiento médico se recurre al tratamiento quirúrgico. La técnica descrita por Tseng basada en el implante de membrana amniótica sin sutura resulta muy eficaz en estos casos debido a la poca inflamación que produce permitiendo una rápida recuperación y mejoría sintomática.Palabras clave: Conjuntivocalasia, membrana amniótica, pegamento de fibrinógeno, sequedad ocular, inflamación. COMUNICACIÓN CORTA ABSTRACTCase report: A 63-year-old man with bilateral conjunctivochalasis presented with tearing, irritation, foreign body sensation and a delayed fluorescein clearance test. After no symptomatic improvement with topical treatment, surgery was carried out, with amniotic membrane transplantation and fibrin sealant. Discussion: Conjunctivochalasis is a frequent disorder that shares symptoms with dry eye syndrome. When there is no response to topical treatment, surgical treatment is needed. The surgical technique described by Tseng, and based on amniotic membrane transplantation without suture, resulted in a very useful response, due to less inflammation and a rapid resolution and improvement of symptoms (Arch Soc Esp Oftalmol 2007; 82: 571-574).

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“…These properties have prompted the use of these membranes in patients with ocular chemical and thermal burns, 27 recurrent pterygia associated with symblepharon, 28 after pterygium excision, in corneal surface reconstruction, 12 revision of leaking blebs after glaucoma surgery, [29][30][31] bullous keratopathy, 32 after surgical treatment of band keratopathy, 33 symptomatic conjunctivochalsis, 34 ulceration of the cornea and sclera, 35 post excimer to reduce corneal haze, 36,3 etc, and more recently for the treatment of symblepharon. 38 Our aim was to study the results of amniotic membrane transplantation in the surgical treatment of symblepharon, to determine the rate of re-epithelization of the amniotic membrane graft, assess incidence of the intra-and postoperative complications encountered, and to observe the recurrence rate of cicatrization following AMT in these eyes.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the outcome of amniotic membrane transplantation for ocular surface reconstruction in symblepharon

Jain

Rastogi

2004

Eye

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Aims Symblepharon is a condition that can inflict serious morbidity on the affected patients. Our aim was to evaluate the efficacy of amniotic membrane transplantation in the surgical treatment of symblepharon by determining the rate of epithelization of the graft, the incidence of complications, and the rate of recurrence of cicatrization. Methods In all, 20 eyes of 18 patients with symblepharon due to various causes and with varied indications for surgery underwent symblepharon excision and amniotic membrane transplantation (AMT). Results We observed recurrence of symblepharon in eight out of the 20 eyes operated upon, but in two of these the cicatrization was focal in nature and did not afford any functional impairment to the patients. Four out of the six eyes that failed had preoperative severe dry eye, and four had undergone previous conjunctival surgery. Conclusions AMT appears to be a safe and effective procedure for the surgical treatment of symblepharon. We observed a 100% rate of epithelization of the graft with no significant postoperative complications and a 30% rate of cicatrization. Pre-existing dry eye and previous conjunctival surgery influence the success of the surgery and these eyes may need medical or surgical supplementation along with AMT to limit the amount of subconjunctival fibrosis for better surgical results.

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Amniotic Membrane Transplantation for Symptomatic Conjunctivochalasis Refractory to Medical Treatments

Abstract: Amniotic membrane transplantation can be considered as an effective means for conjunctival surface reconstruction during removal of conjunctivochalasis.

Cited by 77 publications

References 23 publications

Clinical Impact of Conjunctivochalasis on the Ocular Surface

Clinical Impact of Conjunctivochalasis on the Ocular Surface

Injerto de membrana amniótica con adhesivo tisular en el tratamiento de la conjuntivocalasia refractiva

Evaluation of the outcome of amniotic membrane transplantation for ocular surface reconstruction in symblepharon

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