Amniotic membrane transplantation for acute ocular burns

A case of chemical eye injuries and aspiration pneumonia caused by occupational acute chemical poisoning

“…C hemical eye injuries are an ophthalmic emergency and are responsible for 11.5%-22.1% of eye injuries, [1] and alkaline substances cause more serious injuries than acidic substances. [2] The clinical course of chemical eye injuries can be divided into immediate, acute, early, and late repair stages.…”

“…Heart rhythm was normal, abdomen was soft to touch, and pathological reflex was not induced. The patient was diagnosed with aspiration pneumonia, moderate occupational acute chemical poisoning, [1] and moderate eye burn injuries, according to the China's National Standard Diagnostic Criteria of Occupational Diseases. Betamethasone (10.52 mg) and imipenem (1.0 g) were administered intravenously with intramuscular injection of rat nerve growth factor (30 g).…”

Ocular Chemical Injuries and Limbal Stem Cell Deficiency (LSCD): An Update on Management

“…16,17 A systematic review also failed to find sufficient evidence to definitively support the use of AMT in the treatment of acute ocular burns. 18 AMT also does not appear to be as efficacious in patients with more severe chemical injuries. 10,14,19,20 This may be due to the severity of LSCD in these patients resulting in inability to epithelialize.…”

“…However, 2 randomized clinical trials found no difference in the final visual outcome, corneal clarity, and corneal neovascularization with AMT compared with conventional medical management 16,17 . A systematic review also failed to find sufficient evidence to definitively support the use of AMT in the treatment of acute ocular burns 18 . AMT also does not appear to be as efficacious in patients with more severe chemical injuries 10,14,19,20 .…”