Ammonolysis in Liquid Ammonia.

Alternative One-Pot Synthesis of (Trifluoromethyl)phenyldiazirines from Tosyloxime Derivatives: Application for New Synthesis of Optically Pure Diazirinylphenylalanines for Photoaffinity Labeling

“…Diaziridine 2 was detected as the sole product without 3a , indicating liquid NH 3 was essential for the formation of 3a . On the basis of these results, we postulated that the NH 2 – species generated from liquid NH 3 may be responsible for the formation of TPD 3a , despite liquid NH 3 having a low self-ionization constant (p K a = 27.6 at 25 °C) . A control experiment with NH 4 Cl as an ion counter for inhibiting the self-ionization of liquid NH 3 also confirmed this hypothesis (Table , entry 10).…”

Addition Compounds of Group V Pentahalides

“…RPC14, R2PCI3, and R3PCI2 compounds will react with aluminium trichloride to give 1:1 (and sometimes 1:2, see section IVC) adducts formulated as containing the substituted phosphonium ions RPCI3"1", R2PCI24", and R3PC1+, respectively. Phosphorus pentachloride reacts with N-H bonds with the elimination of HC1 (287) and with ammonia gives poorly characterized P-N compounds (138)…”

THE AMMONOLYSIS OF BENZIL BY LIQUID AMMONIA1

“…Methods for the separation and estimation of these products have been described. 10 For review and primary references see reference 15 3. The Radziszewski glyoxaline synthesis has been shown to result in relatively low yields of lophine when liquid ammonia is used as the reaction medium.…”